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MetabolomicsUntargeted plasma metabolome identifies biomarkers in patients with extracranial arteriovenous malformations

OBJECTIVE: This study aimed to investigate the plasma metabolic profile of patients with extracranial arteriovenous malformations (AVM).

METHOD: Plasma samples were collected from 32 AVM patients and 30 healthy controls (HC). Ultra-high performance liquid c...

2023-10-30 | MTBLS7753 | MetaboLights
TranscriptomicsGlobal gene profiling comparison between hydrogen sulfide- and N-methyl-D-aspartate-induced neuronal deaths
Hydrogen sulfide (H2S), present in abundance in the mammalian brain, has recently been demonstrated to induce a dose- and time-dependent apoptotic-necrotic continuum in murine primary cortical neurons, which was successfully attenuated upon application of N-methyl-D-aspartate (NMDA) receptor antagon...
ORGANISM(S): Mus musculus 
2013-01-23 | E-GEOD-16035 | biostudies-arrayexpress
TranscriptomicsLysine catabolic pathways in P. aeruginosa
Among multiple interconnected pathways for L-Lysine (L-Lys) catabolism in pseudomonads, Pseudomonas aeruginosa PAO1 employed the decarboxylase and the transaminase pathways. However, up till now several genes involved in the operation and regulation of these pathways were still missing. Transcriptom...
ORGANISM(S): Pseudomonas aeruginosa PAO1 
2015-12-09 | E-GEOD-75502 | biostudies-arrayexpress
ProteomicsThe intracellular helical bundle of human glucose transporter GLUT4 is of importance for complex formation with ASPL
DSS-based cross-linking MS of the human glucose transporter GLUT4 in interaction with the human TUG homolog Alveolar Soft Part Sarcoma Locus (ASPL) protein.
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2023-03-27 | MSV000091556 | MassIVE
TranscriptomicsTranscriptome analysis of L-form, protoplast of the B. subtilis cells
To investigate whether the oxidative stress response is induced in protoplasts, we compared the gene expression patterns of protoplasts to those of walled cells and L-forms using microarrays.
ORGANISM(S): Bacillus subtilis 
2015-04-15 | E-MTAB-3380 | biostudies-arrayexpress
TranscriptomicsTriticum aestivum strain:cultivar Transcriptome or Gene expression
The pistillody mutant wheat (Triticum aestivum L.) plant HTS-1 exhibits homeotic transformation of stamens into pistils or pistil-like structures. Unlike common wheat varieties, HTS-1 produces three to six pistils per floret, potentially increasing the yield. Thus, HTS-1 is highly valuable in the st...
ORGANISM(S): Triticum aestivum 
2014-03-14 | E-MTAB-4469 | biostudies-arrayexpress
TranscriptomicsmiRNA profile of microglial cells under oxygen-glucose deprivation
Migroglia cells were exposed to oxygen-glucose deprivation (OGD) for 3 h. The miRNA was isolated and the expression profiles of OGD-activated cells were compared with the profiles of resting cells. Two samples were analysed. miRNAs that were differentially expressed (increased or decreased in expres...
ORGANISM(S): Rattus norvegicus 
2015-11-23 | E-GEOD-63504 | biostudies-arrayexpress
ProteomicsTransfer of the high-quality sugar metabolic model of Aspergillus niger is reliable within the same fungal phylum, but limited for fungi of other phyla
Proteomic data from fungi; intracellular-proteome of five of the studied fungi (A. niger, A. nidulans, P. subrubescens, T. reesei and P. chrysosporium) grown on nine different monosaccharide conditions (L-arabinose, D-fructose, D-galacturonicAcid, D-galactose, D-glucuronicAcid, D-glucose, D-mannose,...
ORGANISM(S): Aspergillus Niger, Aspergillus Nidulans, Penicillium Subrubescens, Trichoderma Reesei, Phanerochaete Chrysosporium 
2022-10-05 | MSV000090477 | MassIVE
MetabolomicsRegulatory T cells promote endurance exercise adaptation by shielding muscle mitochondria from damage

Exercise enhances physical performance and reduces the risk of many disorders such as cardiovascular disease, type 2 diabetes, dementia and cancer. Exercise characteristically incites an inflammatory response, notably in skeletal muscles. While some effector mechanisms have been identified, regul...

2023-10-10 | MTBLS8391 | MetaboLights
TranscriptomicsA high-resolution single-cell multiomic atlas of the human fetal lung - scRNA / GEX / VDJ
We obtained human embryonic and fetal lungs from 5-22 pcw for scRNAseq and scATACseq analysis. To focus on epithelial differentiation and region specialization, we deeply sampled 15, 18, 20 and 22 pcw lungs and separated proximal and distal regions while leaving lungs at 5, 6, 9 and 11 pcw intact. T...
ORGANISM(S): Homo sapiens 
2022-01-27 | E-MTAB-11278 | biostudies-arrayexpress
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