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To investigate whether the oxidative stress response is induced in protoplasts, we compared the gene expression patterns of protoplasts to those of walled cells and L-forms using microarrays.
ORGANISM(S): Bacillus subtilis 
Active genes on the X chromosome of Drosophila males are upregulated by the Male-specific lethal (MSL) complex containing five MSL proteins and two non-coding roX RNAs. To probe the targeting mechanism, we have solved the structure of the MSL3 chromodomain, designed point mutations in key residues t...
ORGANISM(S): Drosophila melanogaster 
Inhibition of proteasome degradation pathway has been implicated in neuronal cell death leading to neurodegenerative diseases such as ParkinsonM-bM-^@M-^Ys disease and AlzheimerM-bM-^@M-^Ys disease. Pharmacological proteasomal inhibitors such as lactacystin can induce apoptosis in cultured mouse co...
ORGANISM(S): Mus musculus 
Genome-wide profiling of histone 3 lysine 4 trimethylation is used for identification of microRNA transcriptional start sites. Various cell types allow a broad range detection of putative promoters rather independent of tissue specific expression patterns. These data are used for identification of ...
ORGANISM(S): Homo sapiens 
We sequenced the total mRNA and translating mRNA (RNC-mRNA) of three hepatocellular carcinoma cell lines Hep3B, HCCLM3 and MHCC97H For each cell line, samples prepared from three independent and identical cell cultures were pooled with equal amounts. C-HPP China Team
ORGANISM(S): Homo sapiens 
Reactive oxygen species (ROS) have been characterized as both important signaling molecules and universal stressors that mediate many developmental and physiological responses. So far, details of the transcriptional mechanism of ROS-responsive genes are still largely unknown. In the study reported h...
ORGANISM(S): Arabidopsis thaliana 
Purified populations of normal human breast luminal and myoepithelial cells were compared with cDNA microarray analysis.
ORGANISM(S): Homo sapiens 
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