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MetabolomicsExogenous L-Alanine promotes phagocytosis multidrug-resistant bacterial pathogens (V. parahaemolyticus-infected spleen metabolomics)

Multidrug-resistant bacteria present a major threat to public health. Therefore, new drugs or approaches are urgently needed to manage and mitigate this threat. Here, we screen the molecular candidates that allow the survival of mice upon Vibrio parahaemolyticus infection by integrated p...

2024-09-26 | MTBLS7996 | MetaboLights
TranscriptomicsIsw2 and Ume6 ChIP-chip in transcription factor deletion (M-NM-^Tume6, M-NM-^Tnrg1, M-NM-^Tcin5, and M-NM-^Tsok2) and DNA-looping deficient (sua7-1) cells
The sequence-specific transcription factors Ume6, Nrg1, Cin5, and Sok2 and the general transcription factor TFIIB mediate the genome-wide targeting of the ATP-dependent chromatin remodeling enzyme Isw2. At least two biological replicates comparing Isw2-ChIP (Isw2-K215R ChIP DNA competitively hybridi...
ORGANISM(S): Saccharomyces cerevisiae 
2013-03-14 | E-GEOD-39542 | biostudies-arrayexpress
no omics definedTranscription profiling of Listeria monocytogenes EGD-e after heat-shock for 3, 10, 20, and 40 min
L. monocytogenes EGD-e (Glaser et al., 2001) was grown in Brain Hearth Infusion Broth (Difco) with shaking (200 rpm, New Brunswick C24KC) using 10 ml culture medium in 100 ml conical flasks. An exponentially growing culture was used to inoculate 100 ml of fresh pre-warmed BHI broth in a 500 ml flask...
ORGANISM(S): Listeria monocytogenes 
2007-10-09 | E-MEXP-1118 | biostudies-arrayexpress
MetabolomicsExogenous L-Alanine promotes phagocytosis multidrug-resistant bacterial pathogens (L-Alanine-treated macrophage metabolomics)

Multidrug-resistant bacteria present a major threat to public health. Therefore, new drugs or approaches are urgently needed to manage and mitigate this threat. Here, we screen the molecular candidates that allow the survival of mice upon Vibrio parahaemolyticus infection by integrated p...

2024-09-26 | MTBLS7986 | MetaboLights
ProteomicsQuantitative chemical proteomics profile target proteins of ITCs
Quantitative chemical proteomics was performed to profile the target proteins of ITCs.For the forward SILAC experiment, heavy-labeled cells were treated with the ITC probe (20 μM) for 30 min and light-labeled cells were pre-treated with the natural ITC (60 μM) for 30 min, followed by the ITC probe (...
ORGANISM(S): Homo sapiens (Human) 
2025-05-06 | PXD051941 | Pride
Human Silac Chemical proteomics Isothiocyanates Hf-x 
MetabolomicsUntargeted plasma metabolome identifies biomarkers in patients with extracranial arteriovenous malformations

OBJECTIVE: This study aimed to investigate the plasma metabolic profile of patients with extracranial arteriovenous malformations (AVM).

METHOD: Plasma samples were collected from 32 AVM patients and 30 healthy controls (HC). Ultra-high performance liquid c...

2023-10-30 | MTBLS7753 | MetaboLights
TranscriptomicsInfluence of BrpA on critical virulence attributes of Streptococcus mutans
Streptococcus mutans, the primary etiological agent of human dental caries, has developed multiple mechanisms to colonize and form biofilms on the tooth surface. The brpA gene codes for a predicted surface-associated protein with apparent roles in biofilm formation, autolysis, and cell division. In ...
ORGANISM(S): Streptococcus mutans 
2008-08-30 | E-GEOD-11773 | biostudies-arrayexpress
TranscriptomicsDynamic profile of gene expression in rice panicle under high temperature
To comprehend the profile of rice gene expression at reproductive stage under high temperature, Agilent 4M-CM-^W44k rice oligo microarray experiments were carried out using rice panicle of developmental stage 7-9 at 0min, 20min, 1hr, 2hr, 4hr, and 8hr after the treatment of 40 degree centigrade, and...
ORGANISM(S): Oryza sativa 
2012-11-28 | E-GEOD-38665 | biostudies-arrayexpress
ProteomicsProteomics study on caffeine for 10 min
Proteomics study on the HepG2 cells which were treated with 6 doses of caffeine for 10 min
ORGANISM(S): Homo Sapiens 
2022-01-14 | PXD030943 |
ProteomicsSystematic analysis of lysine malonylation in Streptococcus mutans
Lysine malonylation is an evolutionarily conserved PTM from bacteria to mammals and involves malonyl-coenzyme (CoA) as a cofactor. Since the malonyl group has an acidic carboxylic group under physiological pH, malonylated lysine is negatively charged, which might impact on protein function and enzym...
ORGANISM(S): Streptococcus mutans UA159 
2022-11-17 | PXD038045 | Pride
Malonylation Biofilm Post-translational modification Streptococcus mutans 
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