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ProteomicsAutophagy Deficiency Promotes Triple-Negative Breast Cancer Resistance to T Cell-Mediated Cytotoxicity by Blocking Tenascin-C Degradation
Most triple-negative breast cancer (TNBC) patients fail to respond to T cell-mediated immunotherapies. Unfortunately, the molecular determinants are still poorly understood. Breast cancer is the disease genetically linked to a deficiency in autophagy. Here, we show that autophagy promotes tumour imm...
ORGANISM(S): Homo sapiens (Human) 
2020-08-05 | PXD019946 | Pride
Tnbc Tenascin-c T cell-mediated killing Autophagy deficiency Immune checkpoint inhibitors 
ProteomicsAutophagy Deficiency Promotes Triple-Negative Breast Cancer Resistance to T Cell-Mediated Cytotoxicity by Blocking Tenascin-C Degradation
Most triple-negative breast cancer (TNBC) patients fail to respond to T cell-mediated immunotherapies. Unfortunately, the molecular determinants are still poorly understood. Breast cancer is the disease genetically linked to a deficiency in autophagy. Here, we show that autophagy promotes tumour imm...
ORGANISM(S): Mus musculus (Mouse) 
2020-08-05 | PXD019947 | Pride
Tnbc Tenascin-c T cell-mediated killing Autophagy deficiency Immune checkpoint inhibitors 
ProteomicsMicroglia cell with light treatment
Explore the protein molecular mechanism of physiological changes in microglia treated with optogenetic technology under light treatment.
ORGANISM(S): Mus musculus (Mouse) 
2024-01-08 | PXD046508 | Pride
Optogenetic Microglia Light treatment 
ProteomicsDIA-Based Quantitative Proteomics Analysis of Human Gastric Cancer Cells
This study investigates the proteomic landscape of AGS gastric cancer cells with stable overexpression of the VASN gene. Utilizing DIA-based quantitative proteomics, we examined protein expression changes in VASN-overexpressing AGS cells compared to their negative control (NC) counterparts. The resu...
ORGANISM(S): Homo sapiens (Human) 
2026-06-29 | PXD058610 | Pride
Cell Dia Gastric Human 
UnknownThe effects of the depth of fertilization on losses of nitrogen and phosphorus and soil fertility in the red paddy soil of China.
Not available
S-EPMC8139273 | biostudies-literature
UnknownTumor microenvironment evaluation promotes precise checkpoint immunotherapy of advanced gastric cancer.
Not available
S-EPMC8356190 | biostudies-literature
UnknownChronic Treatment with Anti-bipolar Drugs Down-Regulates Gene Expression of TRPC1 in Neurones.
Not available
S-EPMC5223735 | biostudies-literature
MetabolomicsMetaboKit: a comprehensive data extraction tool for untargeted metabolomics (Mouse liver assays)

We have developed MetaboKit, a comprehensive software package for compound identification and relative quantification in mass spectrometry-based untargeted metabolomics analysis. In data dependent acquisition (DDA) analysis, MetaboKit constructs a customized spectral library with compound identit...

2021-11-02 | MTBLS1266 | MetaboLights
Proteomicsopd00035_YEAST
DBY8724 yeast cells cultured in YPD medium at 30 deg C (OD600 = 0.8)
ORGANISM(S): Saccharomyces Cerevisiae 
2004-12-31 | PAe000120 | PeptideAtlas
MetabolomicsMetaboKit: a comprehensive data extraction tool for untargeted metabolomics (Standard mixture assay)

We have developed MetaboKit, a comprehensive software package for compound identification and relative quantification in mass spectrometry-based untargeted metabolomics analysis. In data dependent acquisition (DDA) analysis, MetaboKit constructs a customized spectral library with compound identit...

2021-11-05 | MTBLS1311 | MetaboLights
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