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The Ts1Cje mouse strain (Sago, 1998) contains a segmental trisomy of mouse chromosome 16 orthologous to the region of human chromosome 21 commonly associated with Down Syndrome. In this study, fetuses were obtained from wildtype mothers bred with either wildtype or Ts1Cje males. Gene expression prof...
ORGANISM(S): Mus musculus 
We isolated total lung RNA from spontaneously hypertensive male rats 2–40 h after exposure to reference EHC-93. Three animals were exposed to EHC-93 in saline(10 mg/kg body weight) or saline at each time via intratracheal instillation or no instillation at all. RNA from different times was pooled ...
ORGANISM(S): Rattus norvegicus 
Transcriptional responses in lungs of C3H mice infected with Bordetella and mock control
ORGANISM(S): Mus musculus 
Transcriptional responses in lungs of C3H and Hcb28 mice infected with Bordetella and mock control
ORGANISM(S): Mus musculus 
Murine gene expression responses to Bordetella pertussis were determined in lung and spleen, between 0 and 28 days post infection. Data were compared to other parameters such as microarray, flow cytometry, multiplex immunoassays, and lung clearance. A 57 array study with 27 arrays for lung and 30 fo...
ORGANISM(S): Mus musculus 
Hexachlorobenzene (HCB) [CAS:118-74-1; CHEBI:5692] is a persistent environmental pollutant with toxic effects in man and rat. Reported adverse effects are hepatic porphyria, neurotoxicity, and adverse effects on the reproductive and immune system. To obtain more insight into HCB-induced mechanisms o...
ORGANISM(S): Rattus norvegicus 
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