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MetabolomicsToxicometabolomics of the new psychoactive substances α-PBP and α-PEP studied in HepaRG cell incubates by means of untargeted metabolomics revealed unexpected amino acid adducts
Toxicometabolomics, essentially applying metabolomics to toxicology of endogenous compounds such as drugs of abuse or new psychoactive substances (NPS), can be investigated by using different in vitro models and dedicated metabolomics techniques to enhance the number of relevant findings. The presen...
2023-10-10 | MTBLS1481 | MetaboLights
ProteomicsComposition identification of spinach PEP complex
Composition identification of spinach PEP complex by LC-MS/MS
ORGANISM(S): Spinacia Oleracea 
PXD056642 |
ProteomicsStructural basis of chloroplast transcription
Chloroplasts contain a dedicated genome, which encodes subunits of the photosynthesis machinery. Transcription of photosynthesis genes is predominantly carried out by a plastid-encoded RNA polymerase (PEP), a nearly 1 MDa complex composed of core subunits with homology to eubacterial RNA polymerases...
ORGANISM(S): Sinapis alba 
2024-02-19 | PXD048976 | Pride
Plastid encoded rna polymerase Sinapis alba Pep complex Mustard 
ProteomicsStructure of the Plant Plastid-Encoded RNA Polymerase
In this study, the native Sinapis alba plastid-encoded RNA polymerase (PEP) complex was purified and cross-linking MS was used to help in its structure determination.
ORGANISM(S): Sinapis alba 
2024-03-01 | PXD045575 | Pride
Cross-linking Xlms Pep Polymerase Native protein purification 
TranscriptomicsComplex regulation of the PEP carboxykinase gene pck and characterization of its GntR-type regulator IolR as a repressor of myo-inositol utilization genes in Corynebacterium glutamicum
DNA affinity chromatography with the promoter region of the Corynebacterium glutamicum pck gene, encoding phosphoenolpyruvate carboxykinase (PEPCk), led to the isolation of four transcriptional regulators, i.e., RamA, GntR1, GntR2 and IolR. Determination of the PEPCk activity of the deletion mutant...
ORGANISM(S): Corynebacterium glutamicum ATCC 13032 
2013-07-29 | E-GEOD-44812 | biostudies-arrayexpress
ProteomicsQuantitative proteomic analysis of targeted degradation following Pep-TAC treatment
Quantitative proteomic analysis raw data for the manuscript entitled “A covalent peptide-based lysosome-targeting protein degradation platform for cancer immunotherapy”.
ORGANISM(S): Homo Sapiens Mus Musculus 
2025-01-22 | PXD060051 |
ProteomicsCharacterization vy crosslinking-mass spectrometry of plastid-encoded RNA polymerase purified from Sinapis alba.
RNA polymerases (RNAPs) transcribe DNA into RNA and are found in all living organisms with several degrees of complexity from single polypeptide chain to multimeric enzymes. In chloroplast of angiosperms, two RNAPs are involved in plastid gene transcription: the nuclear-encoded RNA polymerase (NEP) ...
ORGANISM(S): Sinapis alba 
2022-09-12 | PXD032739 | Pride
Transcription Photomorphogenesis Photosynthesis Chloroplast biogenesis Pep associated proteins Nanolc-ms/ms Crosslinking Plastid-encoded rna polymerase 
TranscriptomicsChip-chip analysis of C. glutamicum GntR1
The transcriptional regulator GntR1 downregultates the genes for gluconate catabolism and pentose phosphate pathway in Corynebacterium glutamicum. Gluconate lowers the DNA binding affinity of GntR1, which is probably the mechanism of gluconate-dependent induction of these genes. In addition, GntR1 p...
ORGANISM(S): Corynebacterium glutamicum 
2014-07-15 | E-GEOD-58632 | biostudies-arrayexpress
UnknownPEP-FOLD3: faster de novo structure prediction for linear peptides in solution and in complex.
Not available
S-EPMC4987898 | biostudies-literature
ProteomicsMass spectrometry-based proteomic characterization of plastid-encoded RNA polymerase purified from Sinapis alba.
RNA polymerases (RNAPs) transcribe DNA into RNA and are found in all living organisms with several degrees of complexity from single polypeptide chain to multimeric enzymes. In chloroplast of angiosperms, two RNAPs are involved in plastid gene transcription: the nuclear-encoded RNA polymerase (NEP) ...
ORGANISM(S): Sinapis alba 
2022-09-12 | PXD032738 | Pride
Transcription Photomorphogenesis Photosynthesis Chloroplast biogenesis Pep associated proteins Nanolc-ms/ms Plastid-encoded rna polymerase 
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