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ProteomicsBlinded rerun of infected and uninfected pig wound fluids
This is a blinded rerun of 12 pig wound fluid samples from the study at PXD048892, looking at differences in wound fluid peptidomes based on infecting pathogen.The raw data alongside code for easily loading and processing the data and creating relevant figures is available at https://github.com/Fred...
ORGANISM(S): Sus scrofa domesticus (domestic pig) 
2025-05-13 | PXD055074 | Pride
Wound fluid Proteomics Infection Porcine Pig 
ProteomicsBioinformatic analysis of the wound peptidome reveals potential biomarkers and antimicrobial peptides
Peptidomic analysis and methodological development of characterization of low molecular weight peptidome of human wound fluids. Wounds are dynamic environments with high proteolytic activity. Therefore, the study of peptides, being the degradational product of proteins, are of interest when diagnosi...
ORGANISM(S): Homo sapiens (Human) 
2021-01-18 | PXD023244 | Pride
Peptidomics wound fluid 
ProteomicsPeptide clustering enhances large-scale analyses and reveals proteolytic signatures in mass spectrometry data
Recent advances in mass spectrometry-based peptidomics have catalyzed the identification and quantification of thousands of endogenous peptides across diverse biological systems. However, the vast peptidomic landscape generated by proteolytic processing poses several challenges for downstream analys...
ORGANISM(S): Homo sapiens (Human) Sus scrofa domesticus (domestic pig) 
2024-07-13 | PXD048892 | Pride
Peptidomics Wound fluid Peptides Human Infection Porcine 
ProteomicsMethod development and characterization of the low molecular weight peptidome of human wound fluids
Peptidomic analysis and methodological development of characterization of low molecular weight peptidome of human wound fluids and plasma.Data on wound fluid peptides is also found in PXD023244
ORGANISM(S): Homo sapiens (Human) 
2021-09-10 | PXD023884 | Pride
Peptidomics orbitrap 
ProteomicsPeptidomic analysis of bacterial protease activity in acute wound fluids
The clinical assessment of wound infection and related complications is challenging and the development of objective methods to measure wound status and predict healing outcomes is therefore essential. As bacterial protease activities play important roles in infection, analysis of changes in the wou...
ORGANISM(S): Homo sapiens (Human) 
2024-03-07 | PXD037047 | Pride
Human Lc-msms Wound fluids proteases Peptidome 
ProteomicsPeptidomic analysis of endogenous and bacterial protease activity in human plasma
The clinical assessment of wound infection and related complications is challenging and the development of objective methods to measure wound status and predict healing outcomes is therefore essential. As endogenous and bacterial protease activities play important roles in healing and infection, ana...
ORGANISM(S): Homo sapiens (Human) 
2024-03-07 | PXD037245 | Pride
Human Lc-msms Plasma Proteases Peptidome 
ProteomicsProgressive Changes in Human Follicular Fluid Composition over the Course of Ovulation: Quantitative Proteomic Analyses.
The composition of follicular fluid reflects crucial paracrine signalling between granulosa- and theca cells and the oocyte. Dynamic changes in the protein composition of human follicular fluid across multiple time points in the period where final meiotic maturation and release of the oocyte take pl...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2025-02-06 | MSV000097065 | MassIVE
UnknownPeptide clustering enhances large-scale analyses and reveals proteolytic signatures in mass spectrometry data.
Not available
S-EPMC11336174 | biostudies-literature
ProteomicsSynovial fluid proteomics from serial aspiration of ACL injured knees identifies candidate biomarkers for osteoarthritis
Patients with anterior cruciate ligament (ACL) tears have a significantly increased risk for developing knee osteoarthritis. These injuries often result in a knee effusion in response to the injury. Early changes in these effusions could be informative regarding initial steps in the development of...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2022-06-23 | MSV000089716 | MassIVE
ProteomicsGFAP and MBP peptides in Traumatic Brain Injury
Glial fibrillary acidic protein (GFAP) is the major intermediate filament III protein of astroglia cells and is upregulated in astrogliosis following traumatic brain injury (TBI). Here we reported that GFAP is truncated at both the C- and N-terminals by cytosolic protease calpain to GFAP breakdown p...
ORGANISM(S): Homo Sapiens 
2022-07-18 | PXD026550 | panorama
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