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ProteomicsA simplified perchloric acid workflow with neutralization (PCA-N) for democratizing deep plasma proteomics at population scale - Submission04
This project presents PCA-N, a novel plasma proteomics workflow that uses perchloric acid with neutralization to dramatically improve sample preparation efficiency. By eliminating solid-phase extraction and enabling 384-well plate compatibility, PCA-N reduces sample volume requirements to just 5 μL,...
ORGANISM(S): Homo sapiens (Human) 
2025-09-30 | PXD064487 | Pride
Lc-msms Plasma 
ProteomicsA simplified perchloric acid workflow with neutralization (PCA-N) for democratizing deep plasma proteomics at population scale - Submission 5
This project presents PCAᴺ, a novel plasma proteomics workflow that uses perchloric acid with neutralization to dramatically improve sample preparation efficiency. By eliminating solid-phase extraction and enabling 384-well plate compatibility, PCAᴺ reduces sample volume requirements to just 5 μL, c...
ORGANISM(S): Homo sapiens (Human) 
2025-09-30 | PXD064475 | Pride
Lc-msms Plasma 
ProteomicsA simplified perchloric acid workflow with neutralization (PCA N) for democratizing deep plasma proteomics at population scale - Submission02
Large scale plasma proteomics studies offer tremendous potential for biomarker discovery but face significant challenges in balancing analytical depth, throughput and cost effectiveness. We present an optimized perchloric acid based workflow with neutralization – PCA N – that addresses these limitat...
ORGANISM(S): Homo sapiens (Human) 
2025-09-30 | PXD062275 | Pride
Lc-msms Plasma 
ProteomicsA simplified perchloric acid workflow with neutralization (PCA N) for democratizing deep plasma proteomics at population scale - Submission01
Large scale plasma proteomics studies offer tremendous potential for biomarker discovery but face significant challenges in balancing analytical depth, throughput and cost effectiveness. We present an optimized perchloric acid based workflow with neutralization – PCA N – that addresses these limitat...
ORGANISM(S): Homo sapiens (Human) 
2025-09-30 | PXD062274 | Pride
Lc-msms Plasma 
ProteomicsA simplified perchloric acid workflow with neutralization (PCA N) for democratizing deep plasma proteomics at population scale - Submission 3
Large scale plasma proteomics studies offer tremendous potential for biomarker discovery but face significant challenges in balancing analytical depth, throughput and cost effectiveness. We present an optimized perchloric acid based workflow with neutralization – PCA N – that addresses these limitat...
ORGANISM(S): Homo sapiens (Human) 
2025-09-30 | PXD062313 | Pride
Lc-msms Plasma 
UnknownCrystal structure of bis-(1-benzyl-1H-1,2,4-triazole) perchloric acid monosolvate.
Not available
S-EPMC4257456 | biostudies-literature
UnknownElectrochemical Production of Hydrogen Peroxide in Perchloric Acid Supporting Electrolytes for the Synthesis of Chlorine Dioxide.
Not available
S-EPMC8919508 | biostudies-literature
ProteomicsPlasma proteomic, human Ebola virus disease
The 2013-2016 Ebola Zaire virus (EBV) outbreak in West Africa resulted in over 28,000 cases and 11,000 deaths. Ebola virus disease (EVD) is a highly virulent systemic disease with a high case fatality rate of ~ 50%. EVD results in hemorrhagic fever marked by an exaggerated systemic inflammatory resp...
ORGANISM(S): Homo sapiens (Human) 
2022-03-29 | PXD030260 | Pride
Plasma Human Ebola virus disease 
UnknownA Simplified Perchloric Acid Workflow With Neutralization (PCA N) for Democratizing Deep Plasma Proteomics at Population Scale.
Not available
S-EPMC12597270 | biostudies-literature
UnknownUnmasking Heavily O-Glycosylated Serum Proteins Using Perchloric Acid: Identification of Serum Proteoglycan 4 and Protease C1 Inhibitor as Molecular Indicators for Screening of Breast Cancer.
Not available
S-EPMC4758733 | biostudies-literature
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