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TranscriptomicsTranscription profiling of bone marrow samples from human acute myeloid leukemia patients
Gene expression profile of acute myeloid leukemia. Bone marrow (BM) samples from 43 adult patients with newly de novo diagnosed AML.All samples contained more than 80% blast cells. Total RNA was extracted using Trizol reagent (Life Technologies, Gaithersburg, MD) and purified with RNeasy Mini Kit (Q...
ORGANISM(S): Homo sapiens 
2007-08-14 | E-GEOD-1729 | biostudies-arrayexpress
MetabolomicsPeripheral modulation of antidepressant targets MAO-B and GABAAR by harmol induces mitohormesis and delays aging in preclinical models
Reversible and sub-lethal stresses to the mitochondria elicit a program of compensatory responses that ultimately improve mitochondrial function, a conserved anti-aging mechanism termed mitohormesis. Here, we show that harmol, a member of the beta-carbolines family with anti-depressant properties, i...
2023-05-26 | MTBLS7533 | MetaboLights
TranscriptomicsTranscription profiling of mycorrhized European beech (Fagus sylvatica L.) roots in response to fertilization with different forms of inorganic nitrogen
Young Fagus sylvatica trees (approximately 7 to 8 years) were collected from a natural regeneration beech forest. The trees were excavated with intact soil cores, roots and top organic layer. The trees were then kept outdoors at the Department of Forest Botany, Georg-August-Universität Göttingen. Pl...
ORGANISM(S): Fagus sylvatica 
2020-12-14 | E-MTAB-8931 | biostudies-arrayexpress
ProteomicsSecreted folate receptor-gamma drives fibrogenesis in nonalcoholic steatohepatitis by amplifying TGFβ signaling in hepatic stellate cells
Hepatic fibrosis is the primary determinant of mortality in nonalcoholic steatohepatitis (NASH) patients. Antagonism of transforming growth factor (TGF), a master profibrogenic cytokine, is a promising therapeutic target that has not yet been translated into an effective therapy, due in part to the...
ORGANISM(S): Mus musculus (Mouse) Homo sapiens (Human) 
2025-05-06 | PXD035735 | Pride
Proteomics Nonalcoholic steatohepatitis Folate receptor gamma Transforming growth factor beta Hepatic stellate cells 
UnknownGreen synthesis of CaO-Fe₃O₄ composites for photocatalytic degradation and adsorption of synthetic dyes.
Not available
S-EPMC11991969 | biostudies-literature
UnknownNCAPH Drives Breast Cancer Progression and Identifies a Gene Signature that Predicts Luminal A Tumor Recurrence.
Not available
S-EPMC10602143 | biostudies-literature
UnknownMulticenter Phase II Study of Lurbinectedin in BRCA-Mutated and Unselected Metastatic Advanced Breast Cancer and Biomarker Assessment Substudy.
Not available
S-EPMC6209089 | biostudies-literature
UnknownA new case report of severe mucopolysaccharidosis type VII: diagnosis, treatment with haematopoietic cell transplantation and prenatal diagnosis in a second pregnancy.
Not available
S-EPMC6238262 | biostudies-literature
UnknownNCAPH drives breast cancer progression and identifies a gene signature that predicts luminal a tumour recurrence.
Not available
S-EPMC10859882 | biostudies-literature
UnknownStromal SNAI2 Is Required for ERBB2 Breast Cancer Progression.
Not available
S-EPMC7718390 | biostudies-literature
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