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ProteomicsPerilipin 2 mediates milk fat globule secretion
Analysis of the milk fat globule membrane proteome from mice with genetic deletion of Perilipin 2 (Plin2/ADRP/ADPH)
ORGANISM(S): Mus musculus (Mouse) 
2022-10-13 | PXD035020 | Pride
Adrp Perilipin 2 Apocrine secretion Lc ms/ms Proteomics Lactation Lipid droplet Adph Mouse Milk fat globule membrane 
ProteomicsIdiopathic focal segmental glomerulosclerosis plasmas increase lipid droplet formation and perilipin-2 expression in human podocytes
Background: Many patients with idiopathic focal segmental glomerulosclerosis (FSGS) develop recurrence of proteinuria after kidney transplantation. Several circulating permeability factors (CPFs) responsible for recurrence have been suggested, but there is no consensus about the identity of CPFs in ...
ORGANISM(S): Homo sapiens (Human) 
2022-12-22 | PXD028536 | Pride
Circulating permeability factor Podocytes Lipid droplets Perilipin-2 Idiopathic focal segmental glomerulosclerosis (fsgs) 
TranscriptomicsHF liver: Control vs. Plin2-ASO treated
Transcriptional profiling of mouse liver comparing control, scrambled-oligonucleotides (Cont)-treated mice with Perilipin 2-antisense oligonucleotides (Plin2-ASO)-treated mice. C57BL/6 mice on a high-fat diet were treated with oligonucleotides in vivo. The goal was to determine the effects of Plin2 ...
ORGANISM(S): Mus musculus 
2012-12-05 | E-GEOD-37011 | biostudies-arrayexpress
TranscriptomicsSpatial transcriptomic profiling of quadriceps muscles from mice fed either standard diet or high-fat diet for 20 weeks
Intermuscular adipose tissue (IMAT) accumulation within skeletal muscle is associated with cardiometabolic disease, yet its spatial organization and molecular drivers remain poorly characterized. To map IMAT expansion within the quadriceps muscle architecture, spatial transcriptomics was performed o...
ORGANISM(S): Mus musculus 
2026-07-12 | E-MTAB-17271 | biostudies-arrayexpress
TranscriptomicsPerilipin 2 improves insulin sensitivity in skeletal muscle despite elevated intramuscular lipid levels
Type 2 diabetes is characterized by excessive lipid storage in skeletal muscle. Excessive intramyocellular lipid storage exceeds intracellular needs and induces lipotoxic events ultimately contributing to the development of insulin resistance. Lipid droplet (LD)-coating proteins may control proper ...
ORGANISM(S): Mus musculus 
2012-06-08 | E-GEOD-38590 | biostudies-arrayexpress
UnknownImaging cytoplasmic lipid droplets in vivo with fluorescent perilipin 2 and perilipin 3 knock-in zebrafish.
Not available
S-EPMC8460263 | biostudies-literature
TranscriptomicsExpression data from white adipose tissue of Perilipin A transgenic mice
Perilipin A (PeriA) exclusively locates on adipocyte lipid droplets and is essential for lipid storage and lipolysis. Adipocyte specific overexpression of PeriA caused resistance to diet-induced obesity and resulted in improved insulin sensitivity. In order to better understand the biological basis ...
ORGANISM(S): Mus musculus 
2010-05-28 | E-GEOD-21754 | biostudies-arrayexpress
UnknownUCHL1 Regulates Lipid and Perilipin 2 Level in Skeletal Muscle.
Not available
S-EPMC9021748 | biostudies-literature
UnknownInhibition of perilipin 2 expression reduces pro-inflammatory gene expression and increases lipid droplet size.
Not available
S-EPMC6292725 | biostudies-literature
UnknownStudy of the impact of perilipin polymorphisms in a French population.
Not available
S-EPMC1538627 | biostudies-literature
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