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ProteomicsSystematic mapping of the adipocyte plasma membrane proteome reveals KCC1 and PIT2 as novel insulin-responsive transporters
The plasma membrane (PM) is a dynamic interface that integrates environmental cues with cellular responses. Insulin is known to remodel the PM primarily by stimulating the translocation of glucose transporter type 4 (GLUT4), but the full scope of this regulation remains poorly defined. Here, we perf...
ORGANISM(S): Mus musculus (Mouse) 
2026-03-23 | PXD068305 | Pride
UnknownA global checklist of the 932 fruit fly species in the tribe Dacini (Diptera, Tephritidae).
Not available
S-EPMC5799784 | biostudies-literature
UnknownCryotherapy for partial gland ablation of prostate cancer: Oncologic and safety outcomes.
Not available
S-EPMC10166973 | biostudies-literature
UnknownAn OMICs-based meta-analysis to support infection state stratification.
Not available
S-EPMC8388022 | biostudies-literature
TranscriptomicsSystems Toxicology Identifies Mechanistic Impacts of 2-amino-4,6-dinitrotoluene (2-ADNT) Exposure in Northern Bobwhite
A systems toxicology investigation comparing and integrating transcriptomic and proteomic results was conducted to pursue a holistic understanding of the effects of the explosives degradation product 2-amino-4,6-dinitrotoluene (2A-DNT) dosing on the health of the wildlife bird model, Northern bobwhi...
ORGANISM(S): Colinus virginianus 
2015-07-01 | E-GEOD-59910 | biostudies-arrayexpress
UnknownOsteoprotegerin-eluting nanoparticulate mineralized collagen scaffolds improve skull regeneration.
Not available
S-EPMC10089592 | biostudies-literature
TranscriptomicsIdentification of biomarkers that distinguish chemical contaminants using a gradient feature selection method
There are many toxic chemicals to contaminate the world and cause harm to human and other organisms. How to quickly discriminate these compounds and characterize their potential molecular mechanism and toxicity is essential. High through put transcriptomics profiles such as microarray have been prov...
ORGANISM(S): Rattus norvegicus 
2010-01-05 | E-GEOD-19662 | biostudies-arrayexpress
ProteomicsDiversity in pervasive translation. A new translational landscape of yeast.
Pervasive translation is a widespread phenomenon that plays an important role in de novo gene birth; however, its underlying mechanisms remain unclear. Based on multiple Ribosome Profiling datasets, we investigated the translational landscape of coding and noncoding regions of yeast. Therefore, we d...
ORGANISM(S): Saccharomyces cerevisiae (Baker's yeast) 
2024-09-04 | PXD040766 | Pride
Genome evolution Mass spectrometry Non-canonical translation signals De novo coding products Noncoding genome Pervasive translation 
ProteomicsDeletion of the mitochondrial peptidase miPEP in adipose tissue protects against obesity and insulin resistance by increasing adaptive thermogenesis
Mitochondria are pivotal for cellular metabolism, serving as sources and targets of nutrient intermediates from converging metabolic pathways. Here, we demonstrate that insulin resistance leads to a marked alteration in the mitochondrial proteome of adipocytes. Analysis across multiple insulin resis...
ORGANISM(S): Mus musculus (Mouse) 
2024-08-10 | PXD051606 | Pride
Insulin resistance Mipep Thermogenesis Adipose Mitochondria 
UnknownKeratin 13 Is Enriched in Prostate Tubule-Initiating Cells and May Identify Primary Prostate Tumors that Metastasize to the Bone.
Not available
S-EPMC5053503 | biostudies-literature
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