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TranscriptomicsThe non-coding RNA of the multidrug resistance-linked vault particle encodes multiple regulatory small RNAs
Vault particles are conserved organelles that have been implicated in multidrug resistance and intracellular transport. They are formed by three different proteins and the non-coding vault RNAs (vRNAs). Here we show that human vRNAs produce several small RNAs (svRNAs) by mechanisms different from th...
ORGANISM(S): Homo sapiens 
2009-09-07 | E-GEOD-16060 | biostudies-arrayexpress
TranscriptomicsTranscriptional analyses of the ectomycorrhizal (ECM) fungus Paxillus involutus during growth on various lignocellulose soil substrates
In this study, examinations were performed on how the ECM fungus Paxillus involutus degrade complex, plant and litter material by using elemental analyses, FTIR spectroscopy, pyrolysis-GC/MS, and synchronous fluorescence spectroscopy together with microarray analyses screening 12,214 gene models, de...
ORGANISM(S): Paxillus involutus 
2012-02-01 | E-GEOD-34402 | biostudies-arrayexpress
TranscriptomicsThe HER2-encoded miR-4728-3p regulates ESR1 through a non-canonical internal seed interaction
Since the early 1980s remarkable progress has been made in understanding the role of the HER2 locus in carcinogenesis, but many details of its regulatory network are still elusive. We recently reported the finding of 367 new human microRNA (miRNA) genes of which one, mir-4728, is encoded in an intro...
ORGANISM(S): Homo sapiens 
2014-08-13 | E-GEOD-55822 | biostudies-arrayexpress
TranscriptomicsIdentification of new microRNAs in paired normal and tumor breast tissue suggests a dual role for the ERBB2/Her2 gene
To comprehensively characterize microRNA (miRNA) expression in breast cancer, we performed the first extensive next-generation sequencing expression analysis of this disease. We sequenced small RNA from tumors with paired samples of normal and tumor-adjacent breast tissue. Our results indicate that ...
ORGANISM(S): Homo sapiens 
2012-07-06 | E-GEOD-39162 | biostudies-arrayexpress
TranscriptomicsBiobank of Karolinska Endarterectomy (BiKE)
A biobank collection of carotid plaque samples taken from patients undergoing endarterectomy operations. Samples from carotid plaques and peripheral blood mononuclear cells in a setup with clinical registry data collection. See PMID 22371308 for further details.
ORGANISM(S): Homo sapiens 
2012-03-27 | E-GEOD-21545 | biostudies-arrayexpress
UnknownDeclining Antibody Affinity Over Time After Human Vaccination With a Plasmodium falciparum Merozoite Vaccine Candidate.
Not available
S-EPMC11420798 | biostudies-literature
TranscriptomicsDensity Gradients Separate Dormant and Treatment-Resistant Human Glioblastoma Cells
Glioblastoma (GBM) is among the most aggressive cancers. Despite aggressive radiotherapy and treatment with the alkylating agent temozolomide (TMZ), patients ultimately succumb to the disease. Although much interest has focused on highly tumorigenic GBM stem cells (GSCs), adaption of a concept from ...
ORGANISM(S): Homo sapiens 
2016-07-01 | E-GEOD-71116 | biostudies-arrayexpress
TranscriptomicsCarbon availability triggers the decomposition of plant litter and assimilation of nitrogen by an ectomycorrhizal fungus
Abstract: A large part of the nitrogen in forest soils is found in recalcitrant organic matter-protein complexes. Ectomycorrhizal fungi are thought to have a key role in the decomposition and mobilization of nitrogen from such complexes. The knowledge on the functional mechanisms of these processes,...
ORGANISM(S): Paxillus involutus ATCC 200175 
2013-04-30 | E-GEOD-45303 | biostudies-arrayexpress
TranscriptomicsClinically significant copy number alterations and complex rearrangements of MYB and NFIB in adenoid cystic carcinoma of the head and neck
Using high-resolution, array-based comparative genomic hybridization (aCGH), we explored genomic alterations in 40 fresh-frozen ACC samples, the largest cohort to date, with the aims to: (1) identify recurrent CNAs in ACC; (2) identify novel candidate target genes; and (3) correlate recurrent CNAs w...
ORGANISM(S): Homo sapiens 
2012-12-31 | E-GEOD-34816 | biostudies-arrayexpress
UnknownTiming and synchrony of birth in Eurasian lynx across Europe
Not available
S-EPMC9339757 | biostudies-literature
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