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TranscriptomicsTranscription profiling of cultured rat cardiomyocytes grown with eicosapentaenoic acid or docosahexaenoic acid supplementation in the culture media
Despite the recognized protective effects of eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) in cardiovascular diseases, and the demonstration of the control of gene expression by polyunsaturated fatty acids (PUFAs), the effects of these n-3 fatty acids on the whole genoma has never been ...
ORGANISM(S): Rattus norvegicus 
2008-05-07 | E-GEOD-4327 | biostudies-arrayexpress
TranscriptomicsInhibition of MYCN by a PNA anti-gene in alveolar rhabdomyosarcoma
The objective was to identify the molecular mechanisms responsible for in vitro and in vivo efficacy of an anti-MYCN peptide nucleic acid on a preclinical model of alveolar rhabdomyosarcoma. Cells treated with a anti-MYCN PNA exhibit growth arrest and apoptosis, and in vivo tumor growth is blocked. ...
ORGANISM(S): Homo sapiens 
2011-12-31 | E-GEOD-7959 | biostudies-arrayexpress
TranscriptomicsPooled genome-wide analysis to identify novel risk loci for pediatric allergic asthma
We performed a pooled GWAS and individual genotyping in 269 children with allergic respiratory diseases comparing allergic children with and without asthma. We used a modular approach to identify the most significant loci associated with asthma by combining silhouette statistics and physical distanc...
ORGANISM(S): Homo sapiens 
2011-03-17 | E-GEOD-24481 | biostudies-arrayexpress
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