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Bioactive lipid mediators play a crucial role in the induction and resolution of inflammation. To elucidate their involvement during influenza infection, liquid chromatography/mass spectrometry lipidomic profiling of 141 lipid species was performed on a mouse influenza model using two viruses of sig...
2013-05-30 | MTBLS33 | MetaboLights
Ran from polysomes of Lister 427 bloodstream forms, wild-type and a cell line with a double knockout and inducible ZC3H32, grown without tetracycline.
ORGANISM(S): Trypanosoma brucei 
We used five different species of Darwin’s Finches (G. magnirostris, G. conirostris, G. fortis, G. scandens, G. difficilis). G. difficilis was used as a common reference and we polled RNA from 9 unrelated individuals of this species to lower variation. We used at least two unrelated individual embr...
ORGANISM(S): Geospiza magnirostris 
C. elegans mutants deleted for TDP-1, an ortholog of the neurodegeneration-associated RNA binding protein TDP-43, display only mild phenotypes. Nevertheless, transcriptome sequencing revealed that many RNAs were altered in accumulation and/or processing in the mutant. Analysis of these transcription...
ORGANISM(S): Caenorhabditis elegans 
The WHIRLY1 protein, which binds to single stranded DNA in plastids and the nucleus, is involved in chloroplast to nucleus signaling but its precise functions remain to be characterized. Here we investigated WHIRLY1 functions in photosynthesis and nitrogen metabolism using transgenic barley lines (...
ORGANISM(S): Hordeum vulgare 
Cell cycle transitions are regulated by a number of coordinating signaling events. The ubiquitin-proteasome system is an important part of this cell cycle signaling. Cyclin F, a substrate adapter for the SCF (SKP1/CUL1/F-box) E3 ubiquitin ligase, is an important regulator of cell cycle progression. ...
ORGANISM(S): Homo Sapiens (human) 
Skeletal muscle mediates the beneficial effects of exercise, thereby improving insulin sensitivity and reducing the risk for type 2 diabetes. Current skeletal-muscle-models in vitro are incapable of fully recapitulating its physiological functions especially regarding exercise. Supplementation of IG...
ORGANISM(S): Homo sapiens (Human) 
2024-10-17 | PXD043200 | Pride
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