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ProteomicsHigh-resolution proteomic analysis of medulloblastoma clinical samples identifies therapy resistant subgroups and MYC immunohistochemistry as a powerful outcome predictor
While international consensus and the 2021 WHO classification recognize multiple molecular medulloblastoma subgroups, these are difficult to identify in current clinical practice. As a result, biology driven risk stratification and therapy assignment for medulloblastoma constitutes a major challenge...
ORGANISM(S): Homo sapiens (Human) 
2026-02-23 | PXD051235 | Pride
Proteomics Medulloblastoma Myc Immunohistochemistry 
ProteomicsHigh-resolution proteomic analysis of medulloblastoma clinical samples identifies therapy resistant subgroups and MYC immunohistochemistry as a powerful outcome predictor
While international consensus and the 2021 WHO classification recognize multiple molecular medulloblastoma subgroups, these are difficult to identify in current clinical practice. As a result, biology driven risk stratification and therapy assignment for medulloblastoma constitutes a major challenge...
ORGANISM(S): Homo sapiens (Human) 
2025-03-06 | PXD051319 | Pride
Medulloblastoma Dia Proteomics Myc Immunohistochemistry 
ProteomicsMetallothionein immunohistochemistry has high sensitivity and specificity for detection of Wilson disease
Diagnosis of Wilson disease (WD) can be difficult because of its protean clinical presentation, but early diagnosis is important because effective treatment is available and can prevent disease progression. Using quantitative proteomics, we characterized proteins that are differentially expressed in...
ORGANISM(S): Homo sapiens (Human) 
2023-04-18 | PXD029069 | Pride
Quantitative proteomics Immunohistochemistry Liver Wilson disease Mt1g Sensitivity Metallothionein-1g Specificity 
GenomicsMicrosatellite Instability Assessment by Immunohistochemistry in Acute Myeloid Leukemia
Microsatellite Instability Assessment by Immunohistochemistry in Acute Myeloid Leukemia: A Reappraisal and Review of the Literature
PRJEB43843 | ENA
UnknownConventional histological and cytological staining with simultaneous immunohistochemistry enabled by invisible chromogens.
Not available
S-EPMC9042701 | biostudies-literature
GenomicsBone Marrow Microenvironment in Aplastic Anemia: Insights from Nestin/ CXCL12 Immunohistochemistry and RNA-Sequencing
Bone Marrow Microenvironment in Aplastic Anemia: Insights from Nestin/ CXCL12 Immunohistochemistry and RNA-Sequencing
PRJNA1424923 | ENA
UnknownDevelopment of an automated PD-L1 immunohistochemistry (IHC) assay for non-small cell lung cancer.
Not available
S-EPMC4561627 | biostudies-literature
UnknownmTOR Pathway Activation Assessed by Immunohistochemistry in Cervical Biopsies of HPV-associated Endocervical Adenocarcinomas (HPVA): Correlation With Silva Invasion Patterns.
Not available
S-EPMC8349934 | biostudies-literature
ProteomicsThe Proteomic Fingerprint of Prostate Cancer in Primary Tumors and Recurrent Lymph Node Metastases
We performed a quantitative proteome comparison on formalin-fixed paraffin embedded (FFPE) tissue of metastasized and non-metastasized primary prostate cancer (PCa) and on recurrent lymph node metastases. Comparing these three sample groups, we aimed to identify proteins, that might potentially prom...
ORGANISM(S): Homo sapiens (Human) 
2017-12-19 | PXD005833 | Pride
Lymph node metastases Shotgun proteomics Immunohistochemistry Prostate cancer Label free 
ProteomicsProteomic Analysis Based on TMT Regarding the Therapeutic Action of Rhizoma Drynariae on Rats in an Osteoporosis Model
Background: Primary osteoporosis has increasingly become one of the risk factors affecting human health, and the clinical effect and action mechanism of traditional Chinese medicine in the treatment of primary osteoporosis have been widely studied. Previous studies have confirmed that in traditional...
ORGANISM(S): Rattus norvegicus (Rat) 
2024-10-17 | PXD035745 | Pride
Osteoporosis Tmt . Rats Rhizoma drynariae Ovariectomized 
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