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GenomicsAmplicon Sequencing of gRNAs from Brunello CRISPR mutagenized A549 and U87-MG cells after live/dead selection with EV-D68 IL
With the near eradication of poliovirus due to global vaccination campaigns, attention has shifted to other enteroviruses that can cause polio-like paralysis syndrome (now termed acute flaccid myelitis (AFM)). In particular, enterovirus D68 (EV-D68) is believed to be the main driver of epidemic outb...
ORGANISM(S): Homo sapiens 
2025-02-25 | E-MTAB-14765 | biostudies-arrayexpress
MetabolomicsHERPES SIMPLEX VIRUS TYPE 1 IMPAIRS DENDRITIC CELL FUNCTION BY REMODELLING NEUTRAL LIPID METABOLISM AND INDUCING LIPID DROPLET ACCUMULATION
Herpes simplex virus type 1 (HSV-1) infects dendritic cells (DCs), professional antigen-presenting cells that initiate and regulate host antiviral responses. HSV-1 infects DCs limiting their maturation, migration to draining lymph nodes and T cell activation capacity, ultimately promotes their apopt...
2025-04-03 | MTBLS5163 | MetaboLights
TranscriptomicsDNA Methylation Analysis in Human Chorionic Villus and Maternal Blood Cells Using Custom Agilent CGH Arrays
We present a detailed structural and functional analysis of the placental epigenome at its maternal interface. Specifically, we analyzed the DNA methylation pattern of chromsomes 13, 18, and 21 in samples of chorionic villus (CVS) and maternal blood cells (MBC) using custom designed microarrays. We ...
ORGANISM(S): Homo sapiens 
2010-08-27 | E-GEOD-23835 | biostudies-arrayexpress
TranscriptomicsChromatin immunoprecipitation of three PcG proteins and of histone H3 trimethylated at Lys 27 in Drosophila
We determined the distribution of three PcG proteins: PC, PSC and E(Z), and of histone H3 trimethylated at Lys 27 by chromatin immunoprecipitation (ChIP) coupled with analysis of immunoprecipitated DNA with a high density genomic tiling microarray (Affymetrix).
ORGANISM(S): Drosophila melanogaster 
2006-12-30 | E-MEXP-535 | biostudies-arrayexpress
UnknownEarly white matter development is abnormal in tuberous sclerosis complex patients who develop autism spectrum disorder.
Not available
S-EPMC6912944 | biostudies-literature
UnknownHigh vigabatrin dosage is associated with lower risk of infantile spasms relapse among children with tuberous sclerosis complex.
Not available
S-EPMC6347124 | biostudies-literature
UnknownShared molecular neuropathology across major psychiatric disorders parallels polygenic overlap.
Not available
S-EPMC5898828 | biostudies-literature
UnknownPilot Study of Neurodevelopmental Impact of Early Epilepsy Surgery in Tuberous Sclerosis Complex.
Not available
S-EPMC7387194 | biostudies-literature
UnknownTuberous Sclerosis Complex Genotypes and Developmental Phenotype.
Not available
S-EPMC6837240 | biostudies-literature
UnknownResults of the two incidence screenings in the National Lung Screening Trial.
Not available
S-EPMC4307922 | biostudies-literature
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