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TranscriptomicsChromatin immunoprecipitation of human prostate cell lines indicates an H3K4me3/H3K27me3 epigenetic signature of prostate carcinogenesis
This work offers a dynamic picture of epigenetic switches in carcinogenesis and contributes to an overall understanding of coordinated regulation of gene expression in cancer. Our data indicate an H3K4me3/H3K27me3 epigenetic signature of prostate carcinogenesis.
ORGANISM(S): Homo sapiens 
2009-02-12 | E-TABM-635 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of human prostate cell lines to supplement a histone methylation pattern ChIP study
This experiment supplements the 'Histone Methylation pattern ChIP study' with gene expression profiles. These are analyzed in the light of the methylation patterns discovered.
ORGANISM(S): Homo sapiens 
2009-02-05 | E-TABM-634 | biostudies-arrayexpress
TranscriptomicsMoMaTEC1606
Metastatic lesions of endometrial cancer. The data was firstly utilized for identification of highly connected and differentially expressed subnetworks between aggressive primary tumors and metastases. The 66 primary tumor samples have been reused from E-MTAB-2532 using the same prefix (4 digits) of...
ORGANISM(S): Homo sapiens 
2017-12-30 | E-MTAB-5017 | biostudies-arrayexpress
TranscriptomicsMethylation profiling by array of human primary prostate cells during the epithelial to mesenchymal transition
Background: Previously we reported extensive gene expression reprogramming during epithelial to mesenchymal transition (EMT) of primary prostate cells. Here we investigated the hypothesis that specific histone and DNA methylations are involved in coordination of gene expression during EMT and early ...
ORGANISM(S): Homo sapiens 
2010-06-09 | E-TABM-982 | biostudies-arrayexpress
TranscriptomicsChIP- chip by array of human primary prostate cells during the epithelial to mesenchymal transition
Background: Previously we reported extensive gene expression reprogramming during epithelial to mesenchymal transition (EMT) of primary prostate cells. Here we investigated the hypothesis that specific histone and DNA methylations are involved in coordination of gene expression during EMT and early ...
ORGANISM(S): Homo sapiens 
2010-06-09 | E-TABM-983 | biostudies-arrayexpress
TranscriptomicsPrimary Sjogren's syndrome study
The objective of the study was to identify gene expression signatures in minor salivary glands (MSGs) from patients with primary Sjogren's syndrome (SS). METHODS: A 16K complementary DNA microarray was used to generate gene expression profiles in MSGs obtained from 10 patients with primary SS and 10...
ORGANISM(S): Homo sapiens 
2013-11-14 | E-MTAB-2073 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of Atlantic salmon fed with a low, medium or high histidine diet
Atlantic salmon at their 2nd year in sea were fed with a low, medium or high histidine diet (L, M, and H, respectively) for several months. Samples were taken at three time points, after the first, second and third period, and a number of fishes were assigned to a new feed group following a crossove...
ORGANISM(S): Salmon salar 
2009-03-27 | E-TABM-678 | biostudies-arrayexpress
TranscriptomicsMoMaTEC1403
Aim for investigation of expression patterns of endometrial cancers
ORGANISM(S): Homo sapiens 
2014-04-25 | E-MTAB-2532 | biostudies-arrayexpress
TranscriptomicsOncoMap
The aim is to investigate expression patterns of 69 primary tumor samples related to mutation status of FGFR2, KRAS and PIK3CA, and clinico-pathological data.
ORGANISM(S): Homo sapiens 
2013-01-24 | E-MTAB-1358 | biostudies-arrayexpress
TranscriptomicsPRRX1 transcription factor association to type 2 diabetes
Primary human adipose stromal cells (hASCs) from rs4684847 CC risk allele carriers were cultured and induced to differentiate into adipocytes, and simultaneously transfected for 72h with non-targeting siRNA or siRNA targeting PRRX1 (n=10) or both PRRX1 and PPARG (subset of the subjects, n=4).
ORGANISM(S): Homo sapiens 
2013-12-01 | E-MTAB-1906 | biostudies-arrayexpress
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