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TranscriptomicsMicrocolony formation by the opportunistic pathogen Pseudomonas aeruginosa requires pyruvate and pyruvate fermentation.
A hallmark of the biofilm architecture is the presence of microcolonies. However, little is known about the underlying mechanisms governing microcolony formation. In the human pathogen Pseudomonas aeruginosa, microcolony formation is dependent on the two-component regulator MifR, with mifR mutant bi...
ORGANISM(S): Pseudomonas aeruginosa 
2012-04-30 | E-GEOD-35286 | biostudies-arrayexpress
TranscriptomicsPseudomonas aeruginosa two-component regulator BfmR controls bacteriophage lysis and DNA release during biofilm development through PhdA
Biofilms are surface-adhered bacterial communities encased in an extracellular matrix composed of polysaccharides, proteins, and extracelluar (e)DNA, with eDNA being required for the formation and integrity of biofilms. Here we demonstrate that the spatial and temporal release of eDNA is regulated b...
ORGANISM(S): Pseudomonas aeruginosa 
2011-06-01 | E-GEOD-28953 | biostudies-arrayexpress
ProteomicsDistinct lactation-associated macrophages exist in murine mammary tissue and human milk
Macrophages are involved in immune defense, organogenesis and tissue homeostasis. They also contribute to the different phases of mammary gland remodeling during development, pregnancy and involution post-lactation. Yet, less is known about the dynamics of mammary gland macrophages in the lactation ...
ORGANISM(S): Mus musculus (Mouse) 
2023-06-23 | PXD041711 | Pride
Mammary gland Macrophages Lactation Milk 
GenomicsPROX1 ChIP-seq analysis of human colorectal cancer cells SW480R
We performed ChIP-seq data in SW480R cells. Pools of three independent ChIP experiments and input DNA were used for sequencing.
ORGANISM(S): Homo sapiens 
2014-09-18 | E-GEOD-60390 | biostudies-arrayexpress
UnknownSynthesis of morphologically diverse dual thermo- and pH-responsive nano-objects <i>via</i> RAFT-mediated emulsion PISA.
Not available
S-EPMC12584748 | biostudies-literature
TranscriptomicsChIP-chip study aimed at the identification of the repertoire of FOXC2 binding sites affected by the loss of FOXC2 phosphorylation in primary human lymphatic endothelial cells (LECs)
Chromatin immunoprecipitation microarray (ChIP-chip) study using anti-Myc (9E10) antibodies and primary human lymphatic endothelial cells (LECs) transduced with recombinant adenoviruses expressing wild type or phosphorylation-deficient Myc-tagged FOXC2.
ORGANISM(S): Homo sapiens 
2013-07-13 | E-MTAB-596 | biostudies-arrayexpress
TranscriptomicsRNAi knock down using siRNAs targeting PROX1 or §-catenin in human colon carcinoma cells
PROX1 or §-catenin was depleted in SW480 by siRNA transfection and the gene expression profiles were compared to negative controls to study the genes affected.
ORGANISM(S): Homo sapiens 
2018-03-01 | E-MTAB-717 | biostudies-arrayexpress
UnknownAlterations in the Transcriptome of Rye Plants following the Microdochium nivale Infection: Identification of Resistance/Susceptibility-Related Reactions Based on RNA-Seq Analysis.
Not available
S-EPMC8706160 | biostudies-literature
UnknownTTI-621 (SIRPαFc), a CD47-blocking cancer immunotherapeutic, triggers phagocytosis of lymphoma cells by multiple polarized macrophage subsets.
Not available
S-EPMC5662218 | biostudies-literature
UnknownModulation of macrophage antitumor potential by apoptotic lymphoma cells.
Not available
S-EPMC5442466 | biostudies-literature
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