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PeyerM-bM-^@M-^Ys patches (PP) are primary inductive sites of mucosal immunity. Defining PP mononuclear phagocyte system (MPS) is thus crucial to understand the initiation of mucosal immune response. We provide a comprehensive analysis of the phenotype, distribution, ontogeny, lifespan, function and...
ORGANISM(S): Mus musculus 
Phagocyte-Associated Pathobionts in Crohn's Disease
Single-cell RNA profiling of mononuclear phagocyte in colorectal cancer
Murine mononuclear phagocyte lineage cells
During mononuclear phagocyte system evolution, monocytes differentiate into pro-tumorigenic TAMs. We used single cell RNA sequencing (scRNA-seq) to analyze the characteristics of mononuclear phagocyte in colorectal cancer
ORGANISM(S): Homo sapiens 
2023-07-01 | GSE217774 | GEO
This study evaluated lamina propria phagocyte gene expression and the associated microbiome in samples from Crohn's disease patients and controls.
ORGANISM(S): Homo sapiens 
2025-05-22 | GSE267465 | GEO
Gene expression profiling in murine mononuclear phagocyte lineage cells
Mononuclear phagocytes are key regulators of both tissue damage and repair in neuroinflammatory conditions such as multiple sclerosis (MS). To examine divergent phagocyte phenotypes in the inflamed central nervous system (CNS) we introduce an in vivo imaging approach combined with RNAseq and proteom...
ORGANISM(S): Mus musculus (Mouse) 
2019-07-10 | PXD010245 | Pride
The phagocyte NADPH oxidase is critical for host defence, and EROS (Essential for Reactive Oxygen Species) protein is indispensable for expression of its gp91phox-p22phox heterodimer. EROS deficiency in humans is a recently described cause of chronic granulomatous disease (CGD), but its mechanism of...
ORGANISM(S): Mus musculus (Mouse) 
2022-11-30 | PXD025149 | Pride
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