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Staphylococcus aureus is a major human pathogen responsible for severe infections. While traditionally described as extracellular, increasing evidence establishes S. aureus as a facultative intracellular pathogen. Intracellularity contributes to immune evasion, dissemination, and antibiotic failu...

2025-10-26 | MTBLS13220 | MetaboLights
Identification of differentially expressed genes in intestinal phagocytes, compared to non-intestinal cells in Schmidtea mediterranea. Total RNA was isolated from either intestinal phagocytes or non-intestinal cells (control). Four independent biological replicates were conducted with two dye swaps....
ORGANISM(S): Schmidtea mediterranea 
Invertebrates lack the adaptive immune system homologous to that of vertebrates, thus depend exceptionally on the innate immune system for the pathogen recognition and clearance. Phagocytes play a pivotal role in the innate immunity of invertebrates, but the molecular basis underlying their phagocyt...
ORGANISM(S): Crassostrea Gigas 
2018-05-29 | PXD009987 |
The detection of Toll-like receptor 2 (TLR2) expression on E10.5 early embryonic phagocytes prompted us to determine the list of markers co-expressed with TLR2 in a cell-type specific manner. Thus, a comparative expression profiling of cDNAs between murine E10.5 TLR2+ CD11b+ embryonic cells and TLR2...
ORGANISM(S): Mus musculus 
ImmGen ULI: OpenSource Mononuclear Phagocytes Project
Mononuclear phagocytes in neonatal Peyer's patches
Young blood or plasma and young bone marrow improves cognitive function in aged animals, though the cell type responsible for these regenerative effects remains unknown. This study evaluated the potential of induced pluripotent stem cell-derived mononuclear phagocytes (iMPs) as a therapeutic for ag...
ORGANISM(S): Mus musculus (Mouse) 
2025-11-10 | PXD052723 | Pride
Identification of Fcmr-dependent heterogeneity in tumor associated mononuclear phagocytes
Sorted Mouse Phagocytes RNAseq
Mononuclear phagocytes are key regulators of both tissue damage and repair in neuroinflammatory conditions such as multiple sclerosis (MS). To examine divergent phagocyte phenotypes in the inflamed central nervous system (CNS) we introduce an in vivo imaging approach combined with RNAseq and proteom...
ORGANISM(S): Mus musculus (Mouse) 
2019-07-10 | PXD010245 | Pride
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