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TranscriptomicsTranscription profiling of human brains before and after death
An experiment was performed to study effects of death on gene expression in human brain
ORGANISM(S): Homo sapiens 
2006-01-09 | E-TABM-20 | biostudies-arrayexpress
TranscriptomicsTranslocations Activating IRF4 Identify a Subtype of Germinal-Center-Derived B-cell Lymphoma Affecting Predominantly Children and Young Adults
Background: Germinal center B-cell (GCB) lymphomas are common in children and adults. The prognosis strongly depends on age. Subgroups of GCB-lymphomas are characterized by chromosomal translocations affecting immunoglobulin (IG) loci leading to oncogene deregulation. Methods: Novel IG translocation...
ORGANISM(S): Homo sapiens 
2011-06-24 | E-GEOD-22470 | biostudies-arrayexpress
ProteomicsCommensal Clostridiales strains mediate effective anti-cancer immune response against solid tumors
We identified certain members of the gut microbiota associated with a lower tumor burden in mouse models of colorectal cancer (CRC). Orally applied, a mix of four Clostridiales strains (CC4) prevented and even successfully treated CRC as a stand-alone therapy.
ORGANISM(S): Mus Musculus (ncbitaxon:10090) 
2021-06-15 | MSV000087624 | MassIVE
MetabolomicsGNPS - The nutritional and host environment shapes community ecology and keystone functions in a synthetic gut bacterial community
Microbe-microbe interactions are critical for gut microbiome function. A challenging task to understand health and disease-related microbiome signatures is to move beyond descriptive community-level profiling towards disentangling microbial interaction networks. Here, we aimed to determine members t...
ORGANISM(S): Bacteria (ncbitaxon:2) Mus Sp. (ncbitaxon:10095) 
2022-11-14 | MSV000090704 | GNPS
TranscriptomicsTranscriptional Alterations in Bone Marrow Mesenchymal Stromal Cells derived from Acute Myeloid Leukemia patients (AML BM-MSC)
The aim of the study was to get insights into transcriptional alterations in bone marrow mesenchymal stromal cells derived from acute myeloid leukemia patients We compared the global gene expression profile from AML BM-MSC (n=19) to healthy donor (HD) controls (HD BM-MSC n=4) AML BM-MSC and HD BM-MS...
ORGANISM(S): Homo sapiens 
2016-07-27 | E-GEOD-84881 | biostudies-arrayexpress
GenomicsIntegrative analysis of small cell lung cancer
Small-cell lung cancer (SCLC) is an aggressive lung tumor subtype. We conducted integrated analysis of genome sequencing, transcriptome, and copy number analysis and found an extremely high mutation rate of 7.4±1 protein-changing mutations per million basepairs. Evidence for inactivation of TP53 and...
EGAS00001000299 | EGA
TranscriptomicsMolecular alterations in bone marrow mesenchymal stromal cells (BM-MSC) derived from acute myeloid leukemia patients (AML)
Genome wide methylation profiling of BM-MSC derived from AML patients in comparison to healthy donor controls using Illumina Infinium HumanMethylation450 Beadchip bisulfit converted genomic DNA extracted from BM-MSC samples (AML n=32) and healthy donor controls (n=12) were hybridized onto an Illumi...
ORGANISM(S): Homo sapiens 
2016-03-30 | E-GEOD-79695 | biostudies-arrayexpress
Genomicsena-DATASET-RTL-13-12-2013-10:28:27:441-48 - samples
SCLC - Whole genome sequencing data Publication Peifer et al., 2012, Nature Genetics
EGAD00001000703 | EGA
Genomicsena-DATASET-RTL-02-07-2015-13:42:15:919-50 - samples
SCLC - RNA sequencing data Publication Peifer et al., 2012, Nature Genetics
EGAD00001001431 | EGA
GenomicsSCLC_6.0 - samples
SNP 6.0 arrays of small cell lung cancer
EGAD00010000526 | EGA
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