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TranscriptomicsDeregulated expression programs in the hypomorphic Dnmt3b mutant mice
The function of Dnmt3b, of which deregulated activity is linked to several human pathologies, was studied using Dnmt3b hypomorphic mutant mice with reduced catalytic activity. Microarray analysis of deregulated expression programs in the hypomorphic Dnmt3b mutant mice (m3/m24) was combined to an ana...
ORGANISM(S): Mus musculus 
2010-04-21 | E-GEOD-19597 | biostudies-arrayexpress
TranscriptomicsGene array analysis of human CD34+ hematopoietic cells exposed during 24h to HOXB4 or HOXC4 homeoproteins
At the molecular level, the mechanisms of action of Hox genes during hematopoiesis remain elusive. Although reports have described the implication of Hox genes in some molecular pathways in mice, the targets of HOX proteins in human hematopoietic cells are mostly unidentified. Since HOXB4 and HOXC4 ...
ORGANISM(S): Homo sapiens 
2010-10-15 | E-GEOD-24379 | biostudies-arrayexpress
GenomicsWhole genome sequencing of tumour and normal paired samples of diffuse intrinsic pontine gliomas
Diffuse intrinsic pontine glioma (DIPG) have a universally dismal prognosis (median 9-12 months), with neither chemotherapeutic nor targeted agents showing any substantial survival benefit in clinical trials in children with these tumours. DIPG are highly infiltrative malignant glial neoplasms of th...
EGAS00001000572 | EGA
Genomicsena-DATASET-INSTITUTE OF CANCER RESEARCH-17-12-2013-15:22:20:271-113 - samples
Whole exome sequencing of 6 tumour and normal pairs of diffuse intrinsic pontine glioma (DIPG)
EGAD00001000706 | EGA
Genomicsena-DATASET-INSTITUTE OF CANCER RESEARCH-17-12-2013-15:02:33:112-168 - samples
Whole genome sequencing of 20 tumour and normal pairs of diffuse intrinsic pontine glioma (DIPG)
EGAD00001000705 | EGA
GenomicsICR DIPG Data Access Committee
Data Access Committee EGAC00001000148
EGAC00001000148 | EGA
UnknownCase series of intestinal microsporidiosis in non-HIV patients caused by Encephalitozoon hellem.
Not available
S-EPMC10543343 | biostudies-literature
TranscriptomicsIGR_MERCHER_LAM7
Acute megakaryoblastic leukemia (AMKL) is a heterogeneous disease generally associated with poor prognosis. Gene expression profiles indicate the existence of distinct molecular subgroups and several genetic alterations have been characterized in the past years, including the t(1;22)(p13;q13) and th...
ORGANISM(S): Homo sapiens 
2012-11-17 | E-MTAB-1370 | biostudies-arrayexpress
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