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ProteomicsLC7 Proteomic Analysis of Matched Control and NSCLC Lung Adenocarcinoma Tissue.
Non-small cell lung adenocarcinoma is the most frequently diagnosed lung cancer type and remains the leading cause of cancer mortality for men and women in the United States. Management of lung cancer is hindered by high false-positive rates due to the inability to resolve benign versus malignant tu...
ORGANISM(S): Homo sapiens (Human) 
2016-12-23 | PXD002612 | Pride
Human Lc-msms Lung adenocarcinoma Tissue 
ProteomicsAbsolute quantification of human milk caseins and the whey/casein ratio during the first year of lactation
Whey proteins and caseins in breast milk provide bioactivities and also have different amino acid composition. Accurate determination of these two major protein classes will therefore provide a better understanding of human milk composition and function and also aid in developing improved infant for...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2017-06-23 | MSV000081195 | MassIVE
ProteomicsMembrane atg8ylation coordinates stress granule formation and mTOR inactivation in response to lysosomal damage
We report that lysosomal damage is a hitherto unknown inducer of stress granule (SG) formation and that the process termed membrane atg8ylation coordinates SG formation with mTOR inactivation during lysosomal stress. SGs were induced by lysosome-damaging agents including SARS-CoV-2ORF3a, Mycobacteri...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2022-06-09 | MSV000089622 | MassIVE
ProteomicsAtg8ylation coordinates stress granule formation and mTOR inactivation in response to lysosomal damage
Stress granule formation is a part of cellular homeostatic responses, with prototypical inducers being viral infections, heat shock and oxidative damage. Here we show that lysosomal damage is a previously unappreciated robust inducer of stress granule formation interlinked with mTOR inactivation dur...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
MSV000088152 | MassIVE
ProteomicsWhole milk proteome of human and rhesus macaque during peak lactation
Milk has been well established as the optimal nutrition source for infants, yet there is still much to be understood about its molecular composition. Therefore, our objective was to develop and compare comprehensive milk proteomes for human and rhesus macaques to highlight differences in neonatal nu...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) Macaca Mulatta (ncbitaxon:9544) 
2015-02-23 | MSV000079045 | MassIVE
ProteomicsThe 2020 ABRF Beer Study: beer proteomics at the global scale
Beer is one of the oldest and most widely consumed beverages in the world. It contains a complex mixture of proteins from several organisms including plants (barley, hops, rice, wheat) and yeast, depending on the beer. It has been argued that fermentation of grains was responsible for our shift away...
ORGANISM(S): Triticum Aestivum (ncbitaxon:4565) Hordeum Vulgare (ncbitaxon:4513) Oryza Sativa (ncbitaxon:4530) Saccharomyces Cerevisiae (ncbitaxon:4932) Humulus Lupulus (ncbitaxon:3486) 
MSV000088080 | MassIVE
ProteomicsProteomic Characterization of Human Milk Fat Globule Membrane Proteins during a 12 Month Lactation Period
The milk fat globule membrane (MFGM) contains proteins which have been implicated in a variety of health benefits. Milk fat globule membrane proteins were isolated from human milk during a 12 month lactation period and subjected to in solution digestion and liquid chromatography tandem mass spectrom...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2022-06-24 | MSV000089722 | MassIVE
ProteomicsEnvironmental pro-oxidants induce altered envelope protein profiles in human keratinocytes
Cornified envelopes (CEs) of human epidermis consist of transglutaminase-mediated cross-linked proteins and are essential for skin barrier function. Present work explores the influences of pro-oxidant pollutants on the CE protein profiles. In this study, we performed proteomic analysis on CEs induce...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2022-12-14 | MSV000090901 | MassIVE
ProteomicsOmega-6 and omega-3 oxylipins are implicated in soybean oil-induced obesity in mice
Soybean oil consumption is increasing worldwide and parallels the rise in obesity. Rich in unsaturated fats, especially linoleic acid, soybean oil is assumed to be healthy, and yet it induces obesity, diabetes, insulin resistance and fatty liver in mice. Here, we show that the genetically modified s...
ORGANISM(S): Mus Musculus (ncbitaxon:10090) 
2017-06-08 | MSV000081149 | MassIVE
ProteomicsDeep learning neural network prediction method improves proteome profiling of vascular sap of grapevines during Pierces disease development
Plant secretome studies have shown the importance of plant defense proteins in the vascular system against pathogens. Studies on Pierces disease of grapevines caused by the xylem-limited bacteria Xylella fastidiosa Xf have detected proteins and pathways associated to its pathobiology. Despite the bi...
ORGANISM(S): Vitis Vinifera (ncbitaxon:29760) Xylella Fastidiosa Temecula1 (ncbitaxon:183190) 
2020-08-12 | MSV000085942 | MassIVE
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