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ProteomicsFull Mass Range PhiSDM Orbitrap Mass Spectrometry for DIA Proteome Analysis
Optimizing data-independent acquisition (DIA) methods for proteomics applications often requires balancing spectral resolution and acquisition speed. Here we describe the full mass range application of Phase-constrained Spectrum Deconvolution Method (PhiSDM) for OrbitrapTM mass spectrometry in real ...
ORGANISM(S): Homo sapiens (Human) 
2024-01-09 | PXD044292 | Pride
Proteomics Orbitrap High-throughput Data-independent acquisition Phisdm 
ProteomicsDynamic human liver proteome atlas reveals functional insights into disease pathways
Deeper understanding of liver pathophysiology would benefit from a comprehensive quantitative proteome resource at cell-type resolution. Here, we quantify more than 10,000 proteins and 150,000 sequence-unique peptides across total liver, the major liver cell types, time-course of primary cell cultur...
ORGANISM(S): Homo sapiens (Human) 
2022-05-08 | PXD027722 | Pride
Human Atlas Primary cell culture Liver Liver disease Cirrhosis Nash 
ProteomicsStreamlined isolation of the n-terminome
SIMPATICO is a streamlined N-termini proteome workflow which leverages NHS ester chemistry. At the protein level, N-terminal amines (naturally occurring protein N-termini, lysines, or protease-generated N-termini) are blocked directly in the cell lysate, and tryptic digestion is performed straight a...
ORGANISM(S): Homo sapiens (Human) 
2026-09-03 | PXD064097 | Pride
Tmt Lfq Proteolysis N-terminome Degradomics 
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