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ProteomicsSilencing of the PHLDA1 leads to global proteome changes and differentiation pathways of human neuroblastoma cells
Neuroblastoma (NB) is the most common extracranial pediatric solid tumor originating from the abnormal development of cells of the sympathoadrenal lineage of the neural crest. Targeting GD2 ganglioside (GD2), a glycolipid expressed on neuroblastoma cells, with GD2 ganglioside-recognizing antibodies ...
ORGANISM(S): Homo sapiens (Human) 
2024-02-15 | PXD044319 | Pride
Human neuroblastoma cells Gd2 ganglioside-recognizing antibody Mass spectrometry Auts2 Phlda1 silencing 
UnknownSilencing of the PHLDA1 leads to global proteome changes and differentiation pathways of human neuroblastoma cells.
Not available
S-EPMC10941682 | biostudies-literature
UnknownPHLDA1 silencing in IMR-32 human neuroblastoma cells results in ABCB1 overexpression, augments chemoresistance and leads to increased growth of tumors.
Not available
S-EPMC12738729 | biostudies-literature
TranscriptomicsHMF3A_RNAi
HMF3A cells, created from adult human mammary fibroblasts by immortalisation with a thermolabile SV40 large T antigen and the catalytic sub-unit of human telomerase, undergo co-ordinated induction of cellular senescence upon inactivation of T antigen. The pSUPER-retro vector system (Brummelkamp, 200...
ORGANISM(S): Homo sapiens 
2010-06-09 | E-GEOD-690 | biostudies-arrayexpress
UnknownCirc0085539 Promotes Osteosarcoma Progression by Suppressing miR-526b-5p and PHLDA1 Axis.
Not available
S-EPMC7479240 | biostudies-literature
UnknownTranscriptional networks and cellular senescence in human mammary fibroblasts.
Not available
S-EPMC545924 | biostudies-literature
TranscriptomicsHMF3A_with_3Dwt
HMF3A cells, created from adult human mammary fibroblasts by immortalisation with a thermolabile SV40 large T antigen and the catalytic sub-unit of human telomerase, undergo co-ordinated induction of cellular senescence upon inactivation of T antigen. HMF3A cells cease proliferating by 4 days at 39Â...
ORGANISM(S): Homo sapiens 
2010-06-09 | E-GEOD-688 | biostudies-arrayexpress
TranscriptomicsPrim_Fibs
To determine changes in gene expression in primary fibroblasts undergoing replicative senescence, a direct comparison between early passage proliferating cells and senescent cells was performed. Frozen stocks of the primary fibroblasts (HMF3) from which the lines HMF3A and HMF3Dwt were derived (O'Ha...
ORGANISM(S): Homo sapiens 
2010-06-09 | E-GEOD-687 | biostudies-arrayexpress
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