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UnknownUpregulation of phosphatidylinositol glycan anchor biosynthesis class C is associated with unfavorable survival prognosis in patients with hepatocellular carcinoma.
Not available
S-EPMC7856693 | biostudies-literature
UnknownDrosophila models of phosphatidylinositol glycan biosynthesis class A congenital disorder of glycosylation (PIGA-CDG) mirror patient phenotypes.
Not available
S-EPMC10917494 | biostudies-literature
ProteomicsZinc supply mediated by ZNT5-ZNT6 and ZNT7 is critical to glycosylphosphatidylinositol-anchored protein expression
Glycosylphosphatidylinositol (GPI)-anchored proteins play crucial roles in various enzyme activities, cell signaling and adhesion, and immune responses. ZNT type zinc transporter proteins mobilize cytosolic zinc to the extracellular space and intracellular compartments. Here, we report that the earl...
ORGANISM(S): Homo sapiens (Human) 
2022-05-04 | PXD032172 | Pride
Transporter Gpi anchor Er quality control Early secretory pathway Phosphatidylinositol glycan anchor biosynthesis Cell surface Ectoenzyme Zinc Znt 
TranscriptomicsTranscription profiling of mouse GPI-deficient bone marrow cells in a mouse model of targeted Pig-a deletion
Somatic mutation in the X-linked phosphatidylinositol glycan class A (PIG-A) gene causes glycosylphosphatidylinositol (GPI) anchor deficiency in humans with Paroxysmal Nocturnal Hemoglobinuria (PNH). Clinically, patients with PNH have intravascular hemolysis, venous thrombosis and bone marrow failur...
ORGANISM(S): Mus musculus 
2009-09-18 | E-GEOD-14561 | biostudies-arrayexpress
UnknownRole of PIGM and PIGX in glycosylphosphatidylinositol biosynthesis and human health (Review).
Not available
S-EPMC10895387 | biostudies-literature
UnknownCNS glycosylphosphatidylinositol deficiency results in delayed white matter development, ataxia and premature death in a novel mouse model.
Not available
S-EPMC7206848 | biostudies-literature
UnknownReduced cell surface levels of GPI-linked markers in a new case with PIGG loss of function.
Not available
S-EPMC6180480 | biostudies-literature
UnknownParoxysmal Nocturnal Hemoglobinuria: Biology and Treatment.
Not available
S-EPMC10535188 | biostudies-literature
UnknownElimination of GPI2 suppresses glycosylphosphatidylinositol GlcNAc transferase activity and alters GPI glycan modification in Trypanosoma brucei.
Not available
S-EPMC8358704 | biostudies-literature
UnknownParoxysmal nocturnal hemoglobinuria.
Not available
S-EPMC4215311 | biostudies-literature
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