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Sequencing of yeast phosphomutants
Alterations in cell cycle progression caused by S375G and S375E phosphomutants of TDP-43
Protein phosphorylation has a major role in controlling the life-cycle and infection stages of bacteria. Proteome-wide occurrence of S/T/Y phosphorylation has been reported for many prokaryotic systems. Previously, we reported the phosphoproteome of Pseudomonas aeruginosa and Pseudomonas putida. In ...
ORGANISM(S): Pseudomonas aeruginosa PAO1 
2022-03-02 | PXD003645 | Pride
The signal transducer and activator of transcription 3 (STAT3) is a transcription factor mainly activated by phosphorylation in either tyrosine 705 (Y705) or serine 727 (S727) residues that regulates essential processes such as cell differentiation, apoptosis inhibition, or cell survival. we used mi...
ORGANISM(S): Homo sapiens 
2023-11-15 | GSE245862 | GEO
Mitotic entry is accompanyed by the expression of a cluster of so called mitotic genes, whose activation is critical for mitosis in human and yeast cells. We found a link between the transcription machinery and cell cycle control network at mitosis in fission yeast, involving the Cdk8 kinase depende...
ORGANISM(S): Saccharomyces cerevisiae Schizosaccharomyces pombe 
2012-07-13 | GSE31642 | GEO
The generation of distinct cell fates during development depends on asymmetric cell division of progenitor cells. In the central and peripheral nervous system of Drosophila, progenitor cells respectively called neuroblasts or sensory organ precursors use PAR polarity during mitosis to control cell f...
ORGANISM(S): Homo sapiens (Human) Drosophila melanogaster (Fruit fly) 
2024-07-02 | PXD051560 | Pride
An emerging area of TDP-43 is represented by the study of post-translational modifications and the way they are connected to disease-associated mutations. Recently, we described a novel mutation in TDP-43 in an early-onset ALS case that was affecting a potential phosphorylation site in position 375 ...
ORGANISM(S): Homo sapiens 
2022-08-17 | GSE167385 | GEO
Untargeted metabolomics and flux data of E. coli phosphorylation site mutants. Sample description is included in Phosphomutants_file_description.xlsx.
ORGANISM(S): Escherichia Coli (ncbitaxon:562) 
2021-07-12 | MSV000087795 | MassIVE
Mitotic entry is accompanyed by the expression of a cluster of so called mitotic genes, whose activation is critical for mitosis in human and yeast cells. We found a link between the transcription machinery and cell cycle control network at mitosis in fission yeast, involving the Cdk8 kinase depende...
ORGANISM(S): Schizosaccharomyces pombe 
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