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This study addresses this gap by conducting a direct comparison of eight platforms, representing both affinity-based and diverse mass spectrometry approaches, and covering over 13,000 proteins. By applying these platforms to the same cohort, we systematically assess their performance, identifying ke...
ORGANISM(S): Homo sapiens (Human) 
2025-10-09 | PAD000014 | Pride
This study addresses this gap by conducting a direct comparison of eight platforms, representing both affinity-based and diverse mass spectrometry approaches, and covering over 13,000 proteins. By applying these platforms to the same cohort, we systematically assess their performance, identifying ke...
ORGANISM(S): Homo sapiens (Human) 
2025-10-20 | PAD000020 | Pride
Abstract Methylglyoxal is a highly reactive metabolite that is formed spontaneously in the glycolytic pathway. The side chains of various amino acid residues react with methylglyoxal to form advanced-glycation end products (AGEs). This enzyme-independent process introduces post-translational modific...
ORGANISM(S): Homo sapiens (Human) 
2025-11-17 | PXD061990 | Pride
Efficient methods to introduce bioorthogonal groups, such as terminal alkynes, into biomolecules are important tools for chemical biology. State-of-the-art approaches are based on the introduction of a linker between the targeted amino acid and the alkyne, and still present limitations of either rea...
ORGANISM(S): Homo sapiens (Human) 
2020-04-07 | PXD018165 | Pride
Background: Hypertrophic cardiomyopathy (HCM) has traditionally been regarded as a disease of the sarcomere, however it is in the midst of a paradigm shift with growing recognition of contributions beyond the sarcomere to the heterogeneity of HCM phenotypes. Innovative approaches are essential to un...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2025-01-06 | MSV000096785 | MassIVE
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