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MetabolomicsDynamics of Exposure, Phthalates, and Asthma in a Randomized Trial (DEPART)
Not available
ORGANISM(S): Homo sapiens 
ST001317 | MetabolomicsWorkbench
ProteomicsQuantitative Label-free Proteomic Analysis of Ovarian Antral Follicles Exposed In Vivo to a Mixture of Phthalates
Dibutyl phthalate (DBP), di-2-ethylhexyl phthalate (DEHP), and benzyl butyl phthalate (BBP) are three phthalates commonly found in consumer products, including the plastic coating of pharmaceuticals and personal care products. Folliculogenesis, a tightly regulated process occurring in the ovary, is ...
ORGANISM(S): Mus musculus (Mouse) 
2024-07-18 | PXD047061 | Pride
Phthalates Ovarian antral follicles 
ProteomicsEffects of high molecular weight phthalates on LPS-stimulated THP-1 macrophages - proteome
In this study, the effects of three high molecular weight phthalates (DINP, DIDP, DPHP) and their metabolites (MHINP, MCINP, OHMPHP) were investigated in THP-1 macrophages. For this purpose, untargeted proteomics was applied.
ORGANISM(S): Homo sapiens (Human) 
2023-09-13 | PXD043025 | Pride
Thp-1 Mcinp Didp Dinp Ohmphp Dphp Mhinp Proteome 
ProteomicsEffects of high molecular weight phthalates on LPS-stimulated THP-1 macrophages - phosphoproteome
In this study, the effects of three high molecular weight phthalates (DINP, DIDP, DPHP) and their metabolites (MHINP, MCINP, OHMPHP) were investigated in THP-1 macrophages. For this purpose, the phosphoproteome was evaluated.
ORGANISM(S): Homo sapiens (Human) 
2023-09-13 | PXD042912 | Pride
Thp-1 Mcinp Didp Phosphoproteome Dinp Ohmphp Dphp Mhinp 
ProteomicsEffects of high molecular weight phthalates on LPS-stimulated THP-1 macrophages - redoxome
In this study, the effects of three high molecular weight phthalates (DINP, DIDP, DPHP) and their metabolites (MHINP, MCINP, OHMPHP) were investigated in THP-1 macrophages. For this purpose, the redoxome, including overall as well as reversible cysteine oxidation, was evaluated.
ORGANISM(S): Homo sapiens (Human) 
2023-09-13 | PXD043139 | Pride
Thp-1 Mcinp Didp Dinp Ohmphp Dphp Mhinp Redoxome 
TranscriptomicsThe effects of phthalates on S. tropicalis development
Phthalates are added to polymers in order to increase their flexibility, but leach out of the matrix. Given that these plasticizers are mainly found in water bound to particles, aquatic species are exposed to phthalates. Silurana tropicalis eggs were exposed to high concentrations of three pththalat...
ORGANISM(S): Xenopus tropicalis 
2014-07-31 | GSE57675 | GEO
TranscriptomicsRole of PPARalpha in the effects of DEHP on the hepatic expression of a selection of mouse genes
Role of PPARalpha in the effects of DEHP on the hepatic expression of a selection of mouse genes related to nuclear receptor signaling. Di-(2-ethylhexyl)-phthalate (DEHP), a widely used plasticizer, is detected in consumer’s body fluids. Contamination occurs through environmental and food chain s...
ORGANISM(S): Mus musculus 
2010-05-22 | E-GEOD-14920 | biostudies-arrayexpress
TranscriptomicsDiscriminating reprotoxic and non-reprotoxic phthalates by transcriptomics analysis of rat testis
REACH, the EU regulation on chemicals and their safe use, stipulates that about 30,000 chemical substances are to be assessed on their possible risks. Toxicological evaluation of these compounds will at least partly be based on animal testing. Especially reproductive toxicity is one of the most comp...
ORGANISM(S): Rattus norvegicus 
2010-09-01 | GSE20952 | GEO
TranscriptomicsDiscriminating reprotoxic and non-reprotoxic phthalates by transcriptomics analysis of rat testis
REACH, the EU regulation on chemicals and their safe use, stipulates that about 30,000 chemical substances are to be assessed on their possible risks. Toxicological evaluation of these compounds will at least partly be based on animal testing. Especially reproductive toxicity is one of the most comp...
ORGANISM(S): Rattus norvegicus 
2010-08-31 | E-GEOD-20952 | biostudies-arrayexpress
GenomicsXenopus tropicalis
The effects of phthalates on S. tropicalis development
PRJNA247608 | ENA
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