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MetabolomicsL-fucose and fucoidan alleviate high-salt diet-promoted acute inflammation

Excessive salt intake is a widespread health issue observed in almost every country around the world. A high salt diet (HSD) has a strong correlation with numerous diseases, including hypertension, chronic kidney disease and autoimmune disorders. However, the mechanisms underlying HSD-promotion o...

2024-02-21 | MTBLS9134 | MetaboLights
UnknownDevelopment and validation of a nomogram for pressure injury risk prediction in stroke patients: a retrospective cohort study.
Not available
S-EPMC12456027 | biostudies-literature
MetabolomicsMultiomics of synaptic junctions reveals altered lipid metabolism and signaling following environmental enrichment
Membrane lipids and their metabolism have key functions in neurotransmission. Here we provide a quantitative lipid inventory of mouse and rat synaptic junctions. To this end, we developed a multiomics extraction and analysis workflow to probe the interplay of proteins and lipids in synaptic signal t...
2021-09-27 | MTBLS1531 | MetaboLights
ProteomicsSIMPLEX enriches hydrophobic and lipidated proteins in membrane proteomics experiments
Synaptosome (Syn) and synaptic junctions (SJ) are widely used in omics experiments to investigate protein content and networks of synapses. Synapses are a neuronal compartment wit a high lipid content. Liquid-liquid extraction (LLE), typically used in lipidomics, shows great potential for multiomics...
ORGANISM(S): Rattus rattus (Black rat) 
2025-09-08 | PXD058138 | Pride
Liquid-liquid extraction Synaptosomes Domains Synaptic junctions Membrane-enriched sample Transmembrane proteins 
ProteomicsAnalytical Comparison of absolute quantification strategies to investigate the Insulin signaling pathway in fat cells
Mass spectrometry based targeted proteomics is the most sensitive approach to answer and address specific biological questions in an accurate and quantitative fashion. However, the data analysis design used for such quantification varies in the field leading to discrepancies in the reported values. ...
ORGANISM(S): Mus Musculus 
2022-06-13 | PXD026204 | panorama
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