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There is an ongoing discussion about cow’s milk and its variants primarily focusing on the A1 variant in contrast to the A2 variant and their health-related impacts. The difference between these variants lies in a single amino acid alteration at position 67 of β-casein. This alteration is presumed t...
ORGANISM(S): Homo sapiens (Human) 
2026-07-13 | PXD066232 | Pride
Idiosyncratic drug-induced liver injury (iDILI) is a major cause of acute liver failure resulting in liver transplantation or death. Prediction and diagnosis of iDILI remain a great challenge, as current models provide unsatisfying results in terms of sensitivity, specificity and prognostic value. T...
ORGANISM(S): Homo sapiens (Human) 
2018-07-23 | PXD008918 | Pride
Mitochondrial proteins are replete with phosphorylation; however, the origin, abundance, and functional relevance of these modifications are largely unclear. Nonetheless, mitochondria possess multiple resident phosphatases, suggesting that protein dephosphorylation may be broadly important for mitoc...
ORGANISM(S): Mus musculus (Mouse) 
2019-05-29 | PXD012743 | Pride
The discovery of the oncometabolite 2-hydroxyglutarate in isocitrate dehydrogenase 1-mutated (IDH1-mutated) tumor entities affirmed the role of metabolism in cancer. However, large databases with tissue metabolites that are modulated by IDH1 mutation remain an area of development. Here, we present a...
2022-09-07 | MTBLS3873 | MetaboLights
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