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MetabolomicsPlasmodium Niemann-Pick Type C1-Related Protein is a Druggable Target Required for Parasite Membrane Homeostasis
Not available
ORGANISM(S): Plasmodium falciparum 
ST001149 | MetabolomicsWorkbench
GenomicsTargeting postsynaptic glutamate receptor scaffolding proteins PSD-95 and PICK1 for obesity treatment
Targeting postsynaptic glutamate receptor scaffolding proteins PSD-95 and PICK1 for obesity treatment
PRJNA914766 | ENA
ProteomicsRecombinant dimeric PICK1 protein inhibitors for long-term relief of chronic pain by AAV therapeutics
Chronic neuropathic pain’s impact, persistence, and limited treatments render it relevant for gene therapy. Here, we describe the development and application of self-assembling dimeric peptide inhibitors of the pain-associated scaffolding protein PICK1 (protein interacting with C-kinase 1) delivered...
ORGANISM(S): Mus musculus (Mouse) 
2026-04-10 | PXD074049 | Pride
Pick1  protein interacting with c-kinase 1  neuropathic pain Pain treatment  neuropathic pain treatment  gene therapy  aav therapeutics. 
ProteomicsRecombinant dimeric PICK1 protein inhibitors for long-term relief of chronic pain by AAV therapeutics
Chronic neuropathic pain’s impact, persistence, and limited treatments render it relevant for gene therapy. Here, we describe the development and application of self-assembling dimeric peptide inhibitors of the pain-associated scaffolding protein PICK1 (protein interacting with C-kinase 1) delivered...
ORGANISM(S): Mus musculus (Mouse) 
2026-04-10 | PXD073925 | Pride
Pick1  protein interacting with c-kinase 1  neuropathic pain Pain treatment  neuropathic pain treatment  gene therapy  aav therapeutics 
GenomicsTargeting postsynaptic glutamate receptor scaffolding proteins PSD-95 and PICK1 for obesity treatment [2]
Targeting postsynaptic glutamate receptor scaffolding proteins PSD-95 and PICK1 for obesity treatment [2]
PRJNA1055532 | ENA
TranscriptomicsTargeting postsynaptic glutamate receptor scaffolding proteins PSD-95 and PICK1 for obesity treatment [2]
Human genome-wide association studies (GWAS) suggest a functional role for central glutamate receptor signaling and plasticity in body weight regulation. Here, we utilize UK Biobank GWAS summary  statistics of body mass index (BMI) and body fat percentage (BF%) to identify genes encoding for protein...
ORGANISM(S): Mus musculus 
2024-01-04 | GSE251836 | GEO
TranscriptomicsTargeting postsynaptic glutamate receptor scaffolding proteins PSD-95 and PICK1 for obesity treatment
Abstract: Human genome-wide association studies (GWAS) suggest a functional role for central glutamate receptor signaling and plasticity in body weight regulation. Here, we utilize UK Biobank GWAS summary statistics of body mass index (BMI) and body fat percentage (BF%) to identify genes encoding fo...
ORGANISM(S): Mus musculus 
2024-03-11 | GSE221549 | GEO
ProteomicsTargeting postsynaptic glutamate receptor scaffolding proteins PSD-95 and PICK1 for obesity treatment
Human genome-wide association studies (GWAS) suggest a functional role for central glutamate receptor signaling and plasticity in body weight regulation. Here, we utilize UK Biobank GWAS summary statistics of body mass index (BMI) and body fat percentage (BF%) to identify genes encoding for proteins...
ORGANISM(S): Mus musculus (Mouse) 
2024-06-16 | PXD047515 | Pride
Weight-loss Brain 
UnknownC-terminal domain of ICA69 interacts with PICK1 and acts on trafficking of PICK1-PKCα complex and cerebellar plasticity.
Not available
S-EPMC3865253 | biostudies-literature
UnknownThe schizophrenic faces of PICK1.
Not available
S-EPMC3314511 | biostudies-literature
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