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ProteomicsPATIENTS ANTIBODIES RECOGNIZED TWO ISOENZYMES OF GLYCERALDEHYDE -3P- DESHYDROGENASE OF ECHINOCOCCUS GRANULOSUS s. l. Cloning epitopes and enzymatic analysis in silico
Our group is working identifying antigens from E. granulosus s.l by immune-identification and LC-MS/MS methodologies, CE patient sera recognized antigens expressed by cell line from bovine’s protoscolices E .granulouss G1 (EGPE). The antigenic model from EGPE cells showed more sensitivity for patien...
ORGANISM(S): Echinococcus granulosus group 
2025-11-24 | PXD069559 | Pride
Echinococcus granulosus epitopes Glyceraldehyde -3p- deshydrogenase 
ProteomicsMkt1 is required for RNAi-mediated silencing and establishment of heterochromatin in fission yeast
Constitutive domains of repressive heterochromatin are maintained within the fission yeast genome through self-reinforcing mechanisms involving histone methylation and small RNAs. Non-coding RNAs generated from heterochromatic regions are processed into small RNAs by the RNA interference pathway, an...
ORGANISM(S): Schizosaccharomyces pombe 
2019-11-28 | PXD015484 | Pride
Heterochromatin Schizosaccharomyces pombe Rna interference 
ProteomicsFission yeast Caprin protein is required for efficient heterochromatin establishment.
Heterochromatin is a key feature of eukaryotic genomes that serves important regulatory and structural roles in regions such as centromeres. In fission yeast, maintenance of existing heterochromatic domains relies on positive feedback loops involving histone methylation and non-coding RNAs. However,...
ORGANISM(S): Schizosaccharomyces pombe 927 
2025-02-14 | PXD050937 | Pride
Caprin Shotgun proteomics Schizosaccharomyces pombe Rna Heterochromatin Label-free quantitation 
ProteomicsIntegration of JAK/STAT receptor-ligand trafficking, signalling and gene expression in Drosophila melanogaster cells
The JAK/STAT pathway is an essential signalling cascade required for multiple processes during both development and for adult homeostasis. A key question in understanding this pathway is how it is regulated in different cell contexts. Here we have examined how endocytic processing contributes to sig...
ORGANISM(S): Drosophila melanogaster (Fruit fly) 
2020-09-29 | PXD020719 | Pride
Endocytosis Phosphorylation Drosophila Jak/stat signalling Lc-ms/ms 
UnknownUnprecedented toxic blooms of Microcystis spp. in 2019 in the Chowan River, North Carolina.
Not available
S-EPMC11647567 | biostudies-literature
UnknownFour consecutive yearly point-prevalence studies in Wales indicate lack of improvement in sepsis care on the wards.
Not available
S-EPMC8355110 | biostudies-literature
ProteomicsQuantitative proteome profiling of a S-Nitrosoglutathione reductase (GSNOR) null mutant reveals a new class of enzymes involved in nitric oxide homeostasis in plants
Leaves from 4 to 6 week old soil grown WT Col 0 and gsnor1/hot5_2 plants were used for protein extraction. For that, 200mg of plant material was resuspended in extraction buffer (25mM HEPES pH 7.7, 1mM EDTA, 2.5% [w/v] SDS, protease inhibitor cocktail (Pierce A32955)). Following TCA precipitation, p...
ORGANISM(S): Arabidopsis 
2021-08-24 | MSV000088017 | MassIVE
TranscriptomicsThe relationship between inhibition of gastric acid secretion and eradication of Helicobacter pylori
Background: Penicillins inhibit cell wall synthesis; therefore, H. pylori must be dividing for these antibiotics to be effective. Identifying growth responses to varying medium pH may allow design of more effective treatment regimens. Aim: To determine the effect of acidity on bacterial growth and t...
ORGANISM(S): Helicobacter pylori ATCC 43504 
2012-09-30 | E-GEOD-39512 | biostudies-arrayexpress
ProteomicsProlyl hydroxylation regulates protein degradation, synthesis and splicing in human induced pluripotent stem cell-derived cardiomyocytes
Protein hydroxylases are oxygen and alpha-ketoglutarate-dependent enzymes that catalyze hydroxylation of amino acids such as proline, thus linking oxygen and metabolism to enzymatic activity. Prolyl hydroxylation is a dynamic post-translational modification that regulates protein stability and prote...
ORGANISM(S): Homo sapiens (Human) 
2016-05-06 | PXD003621 | Pride
Lc-ms/ms Amino acid labeling Prolyl hydroxylation Ipsc-derived cardiomyocytes 
UnknownValidation of a breast cancer assay for radiotherapy omission: an individual participant data meta-analysis.
Not available
S-EPMC11884857 | biostudies-literature
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