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TranscriptomicsFenofibrate increases VLDL-triglyceride production despite reducing plasma triglyceride levels in APOE*3-Leiden.CETP mice
The PPAR? activator fenofibrate efficiently decreases plasma triglycerides (TG), which is generally attributed to enhanced VLDL-TG clearance and decreased VLDL-TG production. However, since data on the effect of fenofibrate on VLDL production are controversial, we aimed to investigate in (more) deta...
ORGANISM(S): Mus musculus 
2010-05-27 | E-GEOD-21211 | biostudies-arrayexpress
UnknownIn Vivo Magnetic Resonance Imaging-Based Detection of Heterogeneous Endothelial Response in Thoracic and Abdominal Aorta to Short-Term High-Fat Diet Ascribed to Differences in Perivascular Adipose Tissue in Mice.
Not available
S-EPMC7763398 | biostudies-literature
UnknownOncostatin M reduces atherosclerosis development in APOE*3Leiden.CETP mice and is associated with increased survival probability in humans.
Not available
S-EPMC6713386 | biostudies-literature
UnknownThe tyrosine kinase inhibitor nilotinib targets the discoidin domain receptor DDR2 in calcific aortic valve stenosis.
Not available
S-EPMC9544120 | biostudies-literature
TranscriptomicsTranscription profiling of human Rheumatoid arthritis patients to disclose disease pathways in rheumatoid synovium
Rheumatoid arthritis (RA) is a heterogeneous disease. We used cDNA microarray technology to subclassify RA patients and disclose disease pathways in rheumatoid synovium. Hierarchical clustering of gene expression data identified two main groups of tissues (RA-I and RA-II). A total of 121 genes were ...
ORGANISM(S): Homo sapiens 
2005-10-11 | E-SMDB-1874 | biostudies-arrayexpress
TranscriptomicsRheumatoid arthritis and rheumatoid synovium
Rheumatoid arthritis (RA) is a heterogeneous disease. We used cDNA microarray technology to subclassify RA patients and disclose disease pathways in rheumatoid synovium. Hierarchical clustering of gene expression data identified two main groups of tissues (RA-I and RA-II). A total of 121 genes were ...
ORGANISM(S): Homo sapiens 
2005-12-14 | E-GEOD-3824 | biostudies-arrayexpress
UnknownProof-of-concept study for liver-directed miQURE technology in a dyslipidemic mouse model.
Not available
S-EPMC10165407 | biostudies-literature
TranscriptomicsTranscription profiling of synovial tissue mRNA from 21 rheumatoid arthritis patients and 9 osteoarthritis patients vs a common reference sample on lymphochips
Synovial tissue mRNA from 21 RA patients and 9 OA patients is hybridized against a common reference sample on lymphochips.
ORGANISM(S): Homo sapiens 
2005-10-13 | E-SMDB-2032 | biostudies-arrayexpress
TranscriptomicsArthritis and Rheumatism
Synovial tissue mRNA from 21 RA patients and 9 OA patients is hybridized against a common reference sample on lymphochips. Set of arrays organized by shared biological context, such as organism, tumors types, processes, etc. Using regression correlation
ORGANISM(S): Homo sapiens 
2005-12-16 | E-GEOD-3848 | biostudies-arrayexpress
TranscriptomicsFibroblast-like synoviocytes derived from patients with rheumatoid arthritis
Fibroblast-like synoviocytes (FLS) were cultured from synovial tissues from 19 RA patients. RNA was isolated using the Fast Track 2.0 kit (Invitrogen, Carlsbad, California)from the FLS cultures. Fluorescent cDNA probes were prepared from 1 ug experimental mRNA by oligo dT-primed polymerization using...
ORGANISM(S): Homo sapiens 
2006-01-18 | E-GEOD-4061 | biostudies-arrayexpress
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