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MetabolomicsMetabolome of pig endometrium and placenta.

Neonatal mortality is mostly due to a reduced piglet maturity. An essential question for adaptation to extra-uterine environment lies in the optimization of the crosstalk between maternal and fetal genomes for a distribution of resources that allows fetuses to express healthier phenotypes at birt...

2025-06-30 | MTBLS3091 | MetaboLights
MetabolomicsIntegrated microbiome-metabolome-genome axis data of Laiwu and Lulai pigs
Excessive fat deposition can trigger metabolic diseases, and it is crucial to identify factors that can break the link between fat deposition and metabolic diseases. Healthy obese Laiwu pigs (LW) are high in fat content but resistant to metabolic diseases. In this study, we compared the fecal microb...
2023-04-20 | MTBLS3977 | MetaboLights
TranscriptomicsIdentification of global copy number variations among diverse pig breeds by a CGH array
A CNV map in pigs could facilitate the identification of chromosomal regions that segregate for important economic and disease phenotypes. The goal of this study was to identify CNV regions (CNVRs) in pigs based on a custom array comparative genome hybridization (aCGH). We carried out a custom-made ...
ORGANISM(S): Sus scrofa 
2013-08-09 | E-GEOD-41488 | biostudies-arrayexpress
TranscriptomicsComparative analyses of transcriptome during skeletal muscle development between pig breeds differing in muscle growth rate by deep-sequencing
Obese and lean pig show breed-specific traits in muscle growth and meat quality. However, the mechanisms underlying remains unclear. Here, we reported the first genome-wide muscle development research from embryonic to 6 months old between Lantang (obese) and Landrace (lean) using Solexa/Illumina’s ...
ORGANISM(S): Sus scrofa 
2012-06-18 | E-GEOD-25406 | biostudies-arrayexpress
TranscriptomicsA Snapshot of Copy Number Variation in the pig genome
Recents studies in mammalian genomes have uncovered the extent of copy number variation (CNV) that contributes to phenotypic diversity, including health and disease status. Here we report the first glimpse of CNVs in the pig genome covering part of the chromosomes 4, 7, 14 and 17 already sequenced a...
ORGANISM(S): Sus scrofa 
2010-06-21 | E-GEOD-10753 | biostudies-arrayexpress
GenomicsAn atlas of DNA methylomes in pig adipose and muscle tissues
It is evident that epigenetic factors, especially DNA methylation, play essential roles in obesity development. To learn systematic association of DNA methylation to obesity, we used pig as a model, and sampled eight diverse adipose tissues and two distinct skeletal muscle tissues from three pig bre...
ORGANISM(S): Sus scrofa 
2012-05-16 | E-GEOD-30344 | biostudies-arrayexpress
TranscriptomicsRNA-Seq transcriptome profiling of in vitro cultures of migrating porcine primordial germ cells and porcine fetal fibroblasts of mini pig embryos between days 17-24 of gestation
Porcine embryonic germ cells (EGC) are cultured pluripotent cells derived from primordial germ cells (PGC). This study explored the possibilities to establish porcine EGC lines in the domestic breed pig more efficiently and from earlier embryonic stages than reported to date. In vitro culture of PGC...
ORGANISM(S): Sus scrofa 
2011-03-24 | E-GEOD-24220 | biostudies-arrayexpress
TranscriptomicsA Gene Expression Atlas of the Domestic Pig
A Gene Expression Atlas of the Domestic Pig
ORGANISM(S): Sus scrofa 
2012-09-01 | E-MTAB-1183 | biostudies-arrayexpress
GenomicsGenome-wide DNA methylation changes in skeletal muscle between young and middle-aged pigs [methylation]
Background: Age-related physiological, biochemical and functional changes in mammalian skeletal muscle have been shown to begin at the mid-point of the lifespan. However, the underlying changes in DNA methylation that occur during this turning point of the muscle aging process have not been clarifie...
ORGANISM(S): Sus scrofa 
2014-08-02 | E-GEOD-50716 | biostudies-arrayexpress
TranscriptomicsIn vivo gene expression in granulosa cells during pig terminal follicular development.
The aim of this study is the identification of genes and gene networks involved in pig ovarian follicular development. cDNA nylon micro-arrays (2849 sequenced clones) were designed from different libraries : four subtractive suppressive hybridization libraries (generated from small versus large and ...
ORGANISM(S): Sus scrofa 
2008-04-30 | E-GEOD-5798 | biostudies-arrayexpress
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