Sort   by:  
 Page size 
UnknownHrd1-dependent Degradation of the Unassembled PIGK Subunit of the GPI Transamidase Complex.
Not available
S-EPMC10511060 | biostudies-literature
UnknownPIGK defects induce apoptosis in Purkinje cells and acceleration of neuroectodermal differentiation.
Not available
S-EPMC11550446 | biostudies-literature
UnknownIntegrative analysis identifies PIGK as an oncogenic glycosylphosphatidylinositol transamidase subunit with prognostic, immunological, and therapeutic relevance in head and neck cancer.
Not available
S-EPMC12701967 | biostudies-literature
UnknownBi-allelic Variants in the GPI Transamidase Subunit PIGK Cause a Neurodevelopmental Syndrome with Hypotonia, Cerebellar Atrophy, and Epilepsy.
Not available
S-EPMC7118585 | biostudies-literature
ProteomicsProteomic screens of SEL1L-HRD1 ER-associated degradation substrates reveal its vital importance in the biogenesis of glycosylphosphatidylinositol-anchored proteins
The SEL1L-HRD1 protein complex of endoplasmic reticulum (ER)-associated degradation (ERAD) plays indispensable roles for many physiological processes in a substrate-specific manner; however, the nature of endogenous substrates remains largely elusive. Here we have developed a unique proteomics strat...
ORGANISM(S): Homo sapiens (Human) 
2023-12-17 | PXD041882 | Pride
Disease mutants Endogenous substrates Pigk Sel1l-hrd1 erad Proteomic screens Gpi-anchored proteins 
ProteomicsProteomic screens of SEL1L-HRD1 ER-associated degradation substrates reveal its vital importance in the biogenesis of glycosylphosphatidylinositol-anchored proteins
The SEL1L-HRD1 protein complex of endoplasmic reticulum (ER)-associated degradation (ERAD) plays indispensable roles for many physiological processes in a substrate-specific manner; however, the nature of endogenous substrates remains largely elusive. Here we have developed a unique proteomics strat...
ORGANISM(S): Homo sapiens (Human) Mus musculus (Mouse) 
2023-12-17 | PXD041803 | Pride
Endogenous substrates Pigk Disease mutants   Sel1l-hrd1 erad Proteomic screens Gpi-anchored proteins 
UnknownProteomic screens of SEL1L-HRD1 ER-associated degradation substrates reveal its role in glycosylphosphatidylinositol-anchored protein biogenesis.
Not available
S-EPMC10803770 | biostudies-literature
Genomics
RNA-seq for NPC
PRJNA1108057 | ENA
TranscriptomicsGPI transamidase complex is required for primordial germ cell migration and development in zebrafish
Proteins without transmembrane domains could be anchored to the cell surface for regulating various biological processes when covalently linked to glycosylphosphatidylinositol (GPI) molecules by the GPI transamidase (GPIT) complex. However, it remains poorly understood whether and how the GPIT compl...
ORGANISM(S): Danio rerio 
2025-03-28 | GSE263481 | GEO
UnknownFunctional Analysis of the GPI Transamidase Complex by Screening for Amino Acid Mutations in Each Subunit.
Not available
S-EPMC8465894 | biostudies-literature
Sort   by:  
 Page size