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ProteomicsPIK3C3/VPS34 controls Sertoli cell polarity in the mouse testis through the stabilization of the actin cytoskeleton
Sertoli cells are highly polarized testicular cells that provide a nurturing environment for germ cell development and maturation during spermatogenesis. The Class III PI3K, PIK3C3/VPS34 plays key roles in endosomal membrane traffic and macroautophagy in various cell types; however, its role in Sert...
ORGANISM(S): Mus musculus (Mouse) 
2024-08-09 | PXD036240 | Pride
Sertoli cell Cell polarity Autophagy F-actin Spermatogenesis Pik3c3/vps34 
ProteomicsPIK3C3/VPS34 controls Sertoli cell polarity in the mouse testis through the stabilization of the actin cytoskeleton
Sertoli cells are highly polarized testicular cells that provide a nurturing environment for germ cell development and maturation during spermatogenesis. The Class III PI3K, PIK3C3/VPS34 plays key roles in endosomal membrane traffic and macroautophagy in various cell types; however, its role in Sert...
ORGANISM(S): Mus musculus (Mouse) 
2024-08-09 | PXD036242 | Pride
Sertoli cell Cell polarity Autophagy F-actin Spermatogenesis Pik3c3/vps34 
UnknownAutophagy-related protein PIK3C3/VPS34 controls T cell metabolism and function.
Not available
S-EPMC8143264 | biostudies-literature
UnknownRegulation of PIK3C3/VPS34 complexes by MTOR in nutrient stress-induced autophagy.
Not available
S-EPMC4028342 | biostudies-literature
UnknownAn alcoholic extract of Thuja orientalis L. leaves inhibits autophagy by specifically targeting pro-autophagy PIK3C3/VPS34 complex.
Not available
S-EPMC8421415 | biostudies-literature
UnknownDendritic cell PIK3C3/VPS34 controls the pathogenicity of CNS autoimmunity independently of LC3-associated phagocytosis.
Not available
S-EPMC8865280 | biostudies-literature
UnknownCharacterization of Atg38 and NRBF2, a fifth subunit of the autophagic Vps34/PIK3C3 complex.
Not available
S-EPMC5103362 | biostudies-literature
UnknownCritical Role for Phosphatidylinositol-3 Kinase Vps34/PIK3C3 in ON-Bipolar Cells.
Not available
S-EPMC6607926 | biostudies-literature
UnknownClass III phosphatidylinositol 3-kinase complex I subunit NRBF2/Atg38 - from cell and structural biology to health and disease.
Not available
S-EPMC8726667 | biostudies-literature
UnknownBinding of Avibirnavirus VP3 to the PIK3C3-PDPK1 complex inhibits autophagy by activating the AKT-MTOR pathway.
Not available
S-EPMC8386615 | biostudies-literature
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