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ProteomicsQuantitative analysis of redox proteome reveals protein thiol switches regulating fundamental processes in developmental haematopoiesis
Foetal and adult hematopoietic stem and progenitor cells (HSPCs) are characterized by distinct redox homeostasis that may influence their differential cellular behaviour in normal and malignant haematopoiesis. In this work, we have applied a quantitative mass spectrometry-based redox proteomic appro...
ORGANISM(S): Mus musculus (Mouse) 
2022-06-09 | PXD030043 | Pride
Hematopoiesis Leukemia Oxidative modifications Redox proteomics 
ProteomicsQuantitative analysis of redox proteome reveals protein thiol switches regulating fundamental processes in developmental hematopoiesis
Fetal and adult hematopoietic stem and progenitor cells (HSPCs) are characterized by distinct redox homeostasis that may influence their differential cellular behaviour in normal and malignant haematopoiesis. In this work, we have applied a quantitative mass spectrometry-based redox proteomic approa...
ORGANISM(S): Homo sapiens (Human) 
2022-06-09 | PXD033115 | Pride
Oxidative modifications Oxidative stress Redox proteomics Hydrogen peroxide Human embryonic stem cells 
UnknownProteomic analysis of cerebrospinal fluid for relapsing-remitting multiple sclerosis and clinically isolated syndrome.
Not available
S-EPMC4906564 | biostudies-literature
UnknownSTING agonists trigger monocyte death via apoptosis, pyroptosis, caspase-8 activation and mitochondrial dysfunction.
Not available
S-EPMC12579220 | biostudies-literature
UnknownImpact of anesthetics on rat hippocampus and neocortex: A comprehensive proteomic study based on label-free mass spectrometry.
Not available
S-EPMC10950665 | biostudies-literature
UnknownQuantification of cellular protein and redox imbalance using SILAC-iodoTMT methodology.
Not available
S-EPMC6545335 | biostudies-literature
UnknownPeroxiredoxin 6 protects irradiated cells from oxidative stress and shapes their senescence-associated cytokine landscape.
Not available
S-EPMC8688892 | biostudies-literature
UnknownDifferential requirements for Smarca5 expression during hematopoietic stem cell commitment.
Not available
S-EPMC10904812 | biostudies-literature
UnknownQuantitative analysis of redox proteome reveals oxidation-sensitive protein thiols acting in fundamental processes of developmental hematopoiesis.
Not available
S-EPMC9157258 | biostudies-literature
ProteomicsHuman SMARCA5 interactome in transgenic SMARCA5 mouse model
We hypothesize that the ISWI ATPase Smarca5 plays a role in hematopoietic stem cell development via its interaction partners, and to study the role, we used a mouse model with transgenic expression of SMARCA5 coupled with mass spectrometry analysis. The study uses transgenic SMARCA5 mouse model with...
ORGANISM(S): Mus musculus (Mouse) 
2024-06-22 | PXD049034 | Pride
Smarca5 Transgenic mice Immunoprecipitation 
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