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ProteomicsSecretome Comparison of Mesenchymal Stromal Cells and Immature Osteoblasts
Osteoblasts are a key component of the endosteal hematopoietic stem cell (HSC) niche and have long been recognized with strong hematopoietic supporting activity. Osteoblast conditioned media (OCM) enhances the growth of hematopoietic progenitors in culture and modulate their engraftment activity. We...
ORGANISM(S): Homo sapiens (Human) 
2020-07-17 | PXD017372 | Pride
Mesenchymal stromal cells Osteoblasts Secretome 
ProteomicsSecretome Comparison of Mesenchymal Stromal Cells and Immature Osteoblasts
Osteoblasts are a key component of the endosteal hematopoietic stem cell (HSC) niche and have long been recognized with strong hematopoietic supporting activity. Osteoblast conditioned media (OCM) enhances the growth of hematopoietic progenitors in culture and modulate their engraftment activity. We...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2021-11-15 | MSV000088384 | MassIVE
TranscriptomicsTranscription profiling of mouse adult bone marrow cells reveals candidate genes form expansion and transformation of hematopoietic stem cells by NUP98-HOX Fusion Genes
BACKGROUND: Hox genes are implicated in hematopoietic stem cell (HSC) regulation as well as in leukemia development through translocation with the nucleoporin gene NUP98. Interestingly, an engineered NUP98-HOXA10 (NA10) fusion can induce a several hundred-fold expansion of HSCs in vitro and NA10 and...
ORGANISM(S): Mus musculus 
2008-06-17 | E-GEOD-9079 | biostudies-arrayexpress
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