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ProteomicsPirB-CTF LC-MS/MS in hippocampus
Our result indicated PirB could undergo proteolytic process, generating a C-terminal fragment (PirB-CTF). We found PirB-CTF can translocates to the Golgi apparatus, disrupting Golgi-dependent protein transport. To investigate the novel binding partners which mediated the effect of PirB-CTF, we used ...
ORGANISM(S): Mus musculus (Mouse) 
2026-06-08 | PXD063306 | Pride
Mouse Pirb Hippocampus Golgi apparatus C-terminal fragment 
GenomicsNon-alcoholic fatty liver disease exacerbates the advancement of renal fibrosis by modulating renal CCR2+PIRB+ macrophages through the ANGPTL8/PIRB/ALOX5AP axis
Non-alcoholic fatty liver disease exacerbates the advancement of renal fibrosis by modulating renal CCR2+PIRB+ macrophages through the ANGPTL8/PIRB/ALOX5AP axis
PRJNA1184133 | ENA
TranscriptomicsCaSSiDI: Novel single-cell “Cluster Similarity Scoring and Distinction Index” reveals critical functions for PirB and context-dependent Cebpb repression
PirB is an inhibitory cell surface receptor particularly prominent on myeloid cells. PirB curtails the phenotypes of activated macrophages during inflammation or tumorigenesis, but its functions in macrophage homeostasis are obscure. To elucidate PirB-related functions in macrophages at steady-state...
ORGANISM(S): Mus musculus 
2024-01-14 | GSE252466 | GEO
TranscriptomicsNon-alcoholic fatty liver disease exacerbates the advancement of renal fibrosis by modulating renal CCR2+PIRB+ macrophages through the ANGPTL8/PIRB/ALOX5AP axis
Renal fibrosis is a key pathological feature of chronic kidney disease, and non-alcoholic fatty liver disease (NAFLD) is associated with its progression. Our previous experimental results indicate that NAFLD exacerbates UUO-induced renal fibrosis. However, the specific role and mechanisms of NAFLD i...
ORGANISM(S): Mus musculus 
2025-12-17 | GSE281485 | GEO
GenomicsCaSSiDI: Novel single-cell “Cluster Similarity Scoring and Distinction Index” reveals critical functions for PirB and context-dependent Cebpb repression
CaSSiDI: Novel single-cell “Cluster Similarity Scoring and Distinction Index” reveals critical functions for PirB and context-dependent Cebpb repression
PRJNA1060699 | ENA
UnknownLILRB2/PirB mediates macrophage recruitment in fibrogenesis of nonalcoholic steatohepatitis.
Not available
S-EPMC10363120 | biostudies-literature
UnknownElectroacupuncture enhances rehabilitation through miR-181b targeting PirB after ischemic stroke.
Not available
S-EPMC5155251 | biostudies-literature
GenomicsShrimp transcriptome analysis after exposure to recombinant Vibrio parahaemolyticus PirA and PirB toxins
Shrimp transcriptome analysis after exposure to recombinant Vibrio parahaemolyticus PirA and PirB toxins
PRJNA823051 | ENA
UnknownNeuroprotection from stroke in the absence of MHCI or PirB.
Not available
S-EPMC3314229 | biostudies-literature
UnknownStructure and flexibility of the extracellular region of the PirB receptor.
Not available
S-EPMC6433079 | biostudies-literature
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