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MetabolomicsIdentification of chemotypes in bitter melon by metabolomics: a plant with potential benefit for management of diabetes in traditional Chinese medicine

INTRODUCTION: Bitter melon (Momordica charantia, Cucurbitaceae) is a popular edible medicinal plant, which has been used as a botanical dietary supplement for the treatment of diabetes and obesity in Chinese folk medicine. Previously, our team has proved that cucurbitanes triterp...

2019-10-24 | MTBLS701 | MetaboLights
MetabolomicsDiurnal Dynamics Shape Plant Defense Responses: Temporal Variations in Disease Progression and Metabolic Reprogramming in Brassica oleracea
Plants synchronize their immune responses with the circadian cycle, yet the impact of diurnal timing on disease resistance remains poorly understood in crop species. In this study, we investigated how diurnal variation modulates defense responses in Brassica oleracea against Xanthomonas campestris p...
2025-08-22 | MTBLS7854 | MetaboLights
MetabolomicsThe glycosyltransferase UGT76B1 modulates N-hydroxy-pipecolic acid homeostasis and plant immunity
The trade-off between growth and defense is a critical aspect of plant immunity. Therefore, the plant immune response needs to be tightly regulated. Salicylic acid (SA) is an important plant hormone regulating defense against biotrophic pathogens. Recently, N-hydroxy-pipecolic acid (NHP) was identif...
2022-02-28 | MTBLS2334 | MetaboLights
MetabolomicsFrom Herbarium to life: Implications of Reviving Historical Fungi for Modern Plant Pathology and Agriculture.
The Green Revolution (GR) profoundly altered plant–microorganism interactions through widespread agrochemical use and crop breeding. Phytopathogenic fungi present major challenges to agriculture by reducing yield and quality, increasing production costs, and impacting food security and environmental...
2025-06-10 | MTBLS12551 | MetaboLights
MetabolomicsMetabolomic insights into the impact of cooking technologies on plant-based burger composition

This study evaluated the impact of different cooking methods (air frying, grilling, oven baking, and microwave cooking) on the chemical profile of chickpea-based burgers. For this purpose, an untargeted metabolomics approach was employed using ultra-high-performance liquid chromatography coupled ...

2025-08-19 | MTBLS12849 | MetaboLights
MetabolomicsThe Streptomyces-derived nucleoside Guvermectin simultaneously promotes plant growth and immunity

This study investigates the dual role of the Streptomyces-derived nucleoside Guvermectin (GV) in promoting plant growth and enhancing disease resistance. Multiomics analysis revealed that GV reprograms phenylalanine metabolism, leading to the accumulation of antimicrobial flavonoids. A key UDP-gl...

2026-01-31 | MTBLS13810 | MetaboLights
MetabolomicsMetabolite profile data of grapevine plants with brown wood streaking and grapevine leaf stripe (esca complex disease) symptoms

Leaf samples were obtained from Vitis vinifera ‘Malvasia Fina’ plants with well-characterized esca complex disease symptoms (n = 18) and from healthy uninfected plants (n = 6). Leaves from diseased plants were divided into three groups: asymptomatic (ASY), chlorotic (SY1), and scorched leaves (SY...

2021-11-21 | MTBLS353 | MetaboLights
MetabolomicsMechanism of Organic Plant Protection Technology in Controlling Apple Bitter Pit: Insights from Integrated Transcriptomic and Metabolomic Analyses

Apple bitter pit (ABP), a severe physiological disorder, severely impairs the quality and yield of the susceptible 'Qingcui' apple. This study investigated the control efficacy and mechanism of a three-in-one Organic Plant Protection Technology (OPPT) against ABP, with treatments set as control (...

2026-02-26 | MTBLS13937 | MetaboLights
MetabolomicsPenthorum chinense Pursh Ameliorates Metabolic Dysfunction-Associated Alcohol-Related Liver Disease through Gut Microbiota Modulation and Metabolic Remodeling
Metabolic dysfunction-associated alcohol-related liver disease (MetALD) is characterized by hepatic steatosis, oxidative stress, inflammation, and gut microbiota dysbiosis resulting from the coexistence of metabolic dysfunction and alcohol consumption. Penthorum chinense Pursh is a traditional edibl...
2026-06-10 | MTBLS14735 | MetaboLights
MetabolomicsElevated CO2 and virus infection impacts wheat and aphid metabolism

INTRODUCTION: The aphid Rhopalosiphum padi L. is a vector of Barley yellow dwarf virus (BYDV) in wheat and other economically important cereal crops. Increased atmospheric CO2 has been shown to alter plant growth and metabolism, enhancing BYDV disease in wheat. However, the bioch...

2019-01-16 | MTBLS622 | MetaboLights
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