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ProteomicsQuantitative proteome analysis of plasma microparticles for characterization of HCV-induced hepatic cirrhosis and hepatocellular carcinoma
A quantitative label-free proteome analysis was performed using plasma samples from 22 hepatitis-C virus (HCV)-induced liver cirrhosis patients, 16 HCV-positive hepatocellular carcinoma patients with underlying cirrhosis and 18 healthy controls. Plasma microparticles (PMPS) were isolated using ultra...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2020-03-12 | MSV000085094 | MassIVE
ProteomicsPROMIS-Quan: a novel proteomic method for plasma biomarker quantification
Unbiased proteomic analysis of plasma samples holds the promise to reveal clinically invaluable disease biomarkers. However the tremendous dynamic range of the plasma proteome has so far hampered the identification of such low abundant markers. To overcome this challenge we analyzed the plasma micro...
ORGANISM(S): Homo sapiens (Human) 
2015-01-28 | PXD001194 | Pride
Plasma Microparticles Super-silac Biomarkers 
ProteomicsQuantitative proteome analysis of plasma microparticles for characterization of HCV-induced hepatic cirrhosis and hepatocellular carcinoma
A quantitative label-free proteome analysis was performed using plasma samples from 22 hepatitis-C virus (HCV)-induced liver cirrhosis patients, 16 HCV-positive hepatocellular carcinoma patients with underlying cirrhosis and 18 healthy controls. Plasma microparticles (PMPS) were isolated using ultra...
ORGANISM(S): Homo sapiens (Human) 
2017-06-21 | PXD005777 | Pride
Plasma microparticles Liver cirrhosis Hepatitis c virus Label-free proteomics Hepatocellular carcinoma 
TranscriptomicsGenome-wide analysis of the affect of neutrophil-derived microparticles on HUVECs
Analysis of the role of neutrophil-derived microparticles (MP) on gene expression modulation on HUVECs. This study shows that MP can influence gene expression on target cells, demonstrating that these MP are functional entities. Total RNA obtained from HUVECs treated with two different subsets of MP...
ORGANISM(S): Homo sapiens 
2013-05-22 | E-GEOD-25154 | biostudies-arrayexpress
ProteomicsPROMIS-Quan: a novel proteomic method for plasma biomarker quantification
Unbiased proteomic analysis of plasma samples holds the promise to reveal clinically invaluable disease biomarkers. However the tremendous dynamic range of the plasma proteome has so far hampered the identification of such low abundant markers. To overcome this challenge we analyzed the plasma micro...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2017-03-31 | MSV000080835 | MassIVE
OtherPROMIS-Quan: a novel proteomic method for plasma biomarker quantification
Data from ProteomeXchange, PXD ID: PXD001194. File: Animal_20141209_MH_MPs_PC_9.mzml. Published as part of Mol Cell Proteomics. 2015 Jan 26 . From the Abstract: {{i}} To overcome this challenge we analyzed the plasma microparticle proteome, and reached an unprecedented depth of over 3,000 plasma pr...
ORGANISM(S): Homo_sapiens_viruses, Human 
GPM32320007536 | GPMDB
Resource Reanalysis 
ProteomicsCharacterisation of the protein cargo of murine plasma microparticles released during experimental cerebral malaria
Cerebral malaria (CM) is a severe complication of a Plasmodium falciparum infection and is still responsible for a high number of deaths and long term disabilities in children in sub-Saharan Africa. The pathogenesis of this syndrome remains incompletely understood but a number of mechanisms and effe...
ORGANISM(S): Mus musculus (Mouse) 
2016-12-13 | PXD003772 | Pride
Qexactive orbitrap Protein cargo Tandem mass tag (tmt) Microparticles Experimental cerebral malaria 
TranscriptomicsmiRNA expression profiles of Platelet microparticles (PMPs)
To identify the miRNA expressing profiles of Platelet microparticles（PMPs, we have employed the Agilent Human miRNA 8×60K (Design ID:046064) microarray. Platelet microparticles. The platelets were derived from citrated blood of healthy human donors under an Institutional Review Board-approved pro...
ORGANISM(S): Homo sapiens 
2016-01-14 | E-GEOD-76789 | biostudies-arrayexpress
ProteomicsProfiling of Human Circulating Plasma Microparticle Associated Proteins by DDA and DIA
Cells of the vascular system release spherical vesicles, called microparticles (MP), in the size range of 0.1-1μm induced by a variety of stress factors resulting in variable MP concentrations between health and disease. Furthermore, MP have intercellular communication/signaling properties and inter...
ORGANISM(S): Homo sapiens (Human) 
2016-10-18 | PXD003935 | Pride
Human Plasma Microparticles Relative quantification 
UnknownDetermination of the size distribution of blood microparticles directly in plasma using atomic force microscopy and microfluidics.
Not available
S-EPMC3388260 | biostudies-literature
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