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MetabolomicsIndustrial by-products as a novel circular source of biocompatible extracellular vesicles

Extracellular vesicles (EVs) constitute an intricate system of molecular exchange that has recently gained tremendous interest. However, sustainable sources of safe biological EVs remain scarce and elusive. In this study we explore and define the use of food industry byproducts (BP) as a circular...

2022-05-17 | MTBLS2801 | MetaboLights
MetabolomicsmiR-9394b from Lactobacillus paracasei extracellular vesicles targets iNOS to reprogram host NO-ornithine metabolism and ameliorate ulcerative colitis

Background Probiotics have attracted considerable interest for ulcerative colitis (UC); however, their efficacy is highly strain-specific and the underlying molecular mechanisms remain incompletely understood.

Results Accumulating evidence indicates that bacterial extracellular vesicles (BE...

2026-01-23 | MTBLS13753 | MetaboLights
MetabolomicsCharacterization of Whole Blood EVs Using PRotein Organic Solvent PRecipitation

Blood plays a vital role in diagnostic medicine by providing essential information for assessing health and diagnosing various conditions. Routine blood tests can reveal important biomarkers that support early diagnosis and timely intervention. Recently, extracellular vesicles (EVs) have emerged ...

2026-08-24 | MTBLS12801 | MetaboLights
TranscriptomicsExtracellular Vesicles in acute coronary syndrome: carrier of epigenetics marks
Background: Acute coronary syndromes (ACS) are associated with aberrant gene expression and epigenetic mechanisms. In particular, de novo DNA methylation is typically linked to gene silencing, but its role in heart disease remains not fully understood. Extracellular vesicles (EVs) are active compon...
ORGANISM(S): Homo sapiens 
2023-04-03 | E-MTAB-11641 | biostudies-arrayexpress
MetabolomicsCharacterization of small intracellular vesicles uncovers their potential as drug carriers and therapeutic agents

Small extracellular vesicles (sEVs) have been extensively investigated as a source of clinically relevant cargo. Alongside the secretion of EVs, such as exosomes, cells house a multitude of internal vesicles involved in various physiologic processes and metabolic activities. Herein, we developed ...

2025-09-02 | MTBLS12923 | MetaboLights
ProteomicsDiscovery of biomarker proteins in plasma extracellular vesicles from septic patients
Sepsis is a life-threatening condition induced by a dysregulated host response to infection, characterized clinically by systemic inflammation, hemodynamic instability, organ dysfunction, and high mortality. Plasma-derived extracellular vesicles (EVs) have been reported to play a role in mediating p...
ORGANISM(S): Homo sapiens (Human) 
2025-07-14 | PXD056258 | Pride
Proteomics Mass spectrometry Plasma-derived extracellular vesicles (evs) Sepsis Tandem mass tag (tmt) Biomarker 
TranscriptomicsRNA-Seq of tissue and plasma extracellular vesicles of breast cancer patients at the time of diagnosis and after the breast surgery
In the current study, we performed deep sequencing analysis of the RNA cargo of plasma EVs collected at the time of diagnosis, during and after the NAC and up to 18 months after the surgery and matched tumor and normal tissues from 35 patients with locally advanced BC, and 30 cancer-free females.
ORGANISM(S): Homo sapiens 
2022-10-24 | E-MTAB-12014 | biostudies-arrayexpress
ProteomicsProteomic analysis of plasma-derived extracellular vesicles: pre- and postprandial comparisonsProteomic analysis of plasma-derived extracellular vesicles: pre- and postprandial comparisons
Extracellular vesicles (EVs) are key in intercellular communication, carrying biomolecules like nucleic acids, lipids, and proteins. This study investigated postprandial characteristics and proteomic profiles of plasma-derived large extracellular vesicles (lEVs) in healthy individuals. Twelve partic...
ORGANISM(S): Homo sapiens (Human) 
2025-05-07 | PXD055597 | Pride
Proteomics Fasting Postprandial Extracellular vesicles Plasma Liquid biopsy 
UnknownPlasma-derived extracellular vesicles (EVs) as biomarkers of sepsis in burn patients via label-free Raman spectroscopy.
Not available
S-EPMC11529045 | biostudies-literature
ProteomicsProteomic and bioinformatic characterization of extracellular vesicles released from human primary macrophages upon influenza A infection
We have previously shown that IAV infection of human monocyte-derived macrophages causes major alterations to subcellular protein trafficking inside the cell and triggers robust protein secretion (Lietzén et al, 2011). Here, we have used high-throughput proteomics to identify proteins secreted in ex...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2017-03-16 | MSV000080643 | MassIVE
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