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In vitro model of differentiation of memory B cells into plasmablasts and plasma cells.
ORGANISM(S): Homo sapiens 
The mammalian CCCTC-binding factor (CTCF) regulates gene expression through the formation of higher order chromatin structures. Recent evidence has implicated a role for CTCF in regulating gene expression in the human MHCII locus. To investigate the role of CTCF in murine MHCII gene expression we ...
ORGANISM(S): Mus musculus 
We report the genome-wide mapping of 5hmC in naive B cells and in vitro differentiated plasmablasts (P1 cells). In addition, H3K4me1 and H3K27ac histne marks were mapped in in vitro differentiated plasmablasts from two healthy donors (BN358 and BN369) by ChIP-seq. Genomic DNA from human primary cell...
ORGANISM(S): Homo sapiens 
Transcriptional changes upon Jagn1 loss in LPS-stimulated plasmablasts.
Immunophenotyping and transcriptional profiling of human plasmablasts in dengue.
To study longitudinal dynamics of IGH BCR repertoires and clonal lineages evolution of memory B-cells, plasmablasts and plasma cells from peripheral blood of healthy donors, which were sampled three times within a year
ORGANISM(S): Homo sapiens 
CD27hiCD38hi plasmablasts are activated B cells of mixed origin with distinct function [Smart-seq]
CD27hiCD38hi plasmablasts are activated B cells of mixed origin with distinct function [10X Genomics]
Plasma cells (PCs) as effectors of humoral immunity produce immunoglobulins to match pathogenic insult. However, emerging data suggests more diverse roles for PCs as regulators of immune and inflammatory responses via secretion of factors other than immunoglobulins. The extent to which such response...
ORGANISM(S): Homo sapiens 
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