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ProteomicsPlasmodium falciparum PM X LC-MSMS
Plasmepsin X (PM X) is an aspartate protease expressed in the malaria parasie Plasmodium falciparum. Following synthesis PM X undergoes proteolytic processing. This project aims to understand the significance of PM X processing. To identify the cleavage sites, the processed PM X bands were excised f...
ORGANISM(S): Plasmodium falciparum (isolate 3D7) 
2022-10-14 | PXD035172 | Pride
Lc-msms Malaria Plasmepsin x Plasmodium 
ProteomicsPlasmepsin X activates function of the PCRCR complex in P. falciparum by processing PfRh5 for binding to basigin and invasion of human erythrocytes
Plasmodium falciparum causes the most severe form of malaria in humans. The protozoan parasite develops within erythrocytes to mature schizonts, that contain more than 16 merozoites, which egress and invade fresh erythrocytes. The aspartic protease plasmepsin X (PMX), processes proteins and protease...
ORGANISM(S): Plasmodium falciparum (isolate 3D7) 
2023-04-05 | PXD039646 | Pride
Malaria Plasmepsin x Ip-ms Pcrcr 
GenomicsDual plasmepsin IX and X inhibitors are refractory to development of resistance
Dual plasmepsin IX and X inhibitors are refractory to development of resistance in malaria Plasmodium falciparum
PRJEB107760 | ENA
UnknownStructure-activity analysis of imino-pyrimidinone-fused pyrrolidines aids the development of dual plasmepsin V and plasmepsin X inhibitors.
Not available
S-EPMC12138161 | biostudies-literature
UnknownSubstrate Peptidomimetic Inhibitors of P. falciparum Plasmepsin X with Potent Antimalarial Activity.
Not available
S-EPMC9804387 | biostudies-literature
UnknownMaturation and substrate processing topography of the Plasmodium falciparum invasion/egress protease plasmepsin X.
Not available
S-EPMC9352755 | biostudies-literature
UnknownCrystallization and preliminary X-ray analysis of the aspartic protease plasmepsin 4 from the malarial parasite Plasmodium malariae.
Not available
S-EPMC1952262 | biostudies-literature
UnknownPlasmepsin X activates the PCRCR complex of Plasmodium falciparum by processing PfRh5 for erythrocyte invasion.
Not available
S-EPMC10113190 | biostudies-literature
UnknownMacrocyclic Peptidomimetic Plasmepsin X Inhibitors with Potent In Vitro and In Vivo Antimalarial Activity.
Not available
S-EPMC10424242 | biostudies-literature
UnknownDiscovery and Characterization of Potent, Efficacious, Orally Available Antimalarial Plasmepsin X Inhibitors and Preclinical Safety Assessment of UCB7362.
Not available
S-EPMC9620073 | biostudies-literature
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