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TRAIL cytotoxicity is exploited as anti-cancer therapy since many years, however incomplete knowledge is generating many obstacles. Here, we address whether the highly abundant extracellular matrix molecule tenascin-C (TNC) orchestrating an immune suppressive tumor microenvironment and binding TRAIL...
ORGANISM(S): Mus musculus (Mouse) 
2026-04-15 | PXD045388 | Pride
Purpose: To elucidate the potential immune-regulatory mechanism of TRAIL of activated T cells in EAE, we analyzed gene expression profiles of splenic CD4+ T cells from EAE mice treated with TRAIL by RNA sequencing and transcriptome analysis. Methods: Splenic CD4+ T cell mRNA profiles of control or E...
ORGANISM(S): Mus musculus 
2017-12-27 | GSE108523 | GEO
Next generation sequencing analysis of gene expression profiles in splenic CD4+ T cells from EAE mice treated with TRAIL
In order to test the usability of the new MS feature detection algorithm Dinosaur, 8 samples were analyzed. These were selected to represent different proteomics experiments and cover the full range of sample different complexities, from synthetic peptides to whole tissue lysate. This project evolve...
ORGANISM(S): Mus musculus (Mouse) Homo sapiens (Human) Streptococcus pyogenes serotype M1 (strain ATCC BAA-947 / MGAS5005) 
2016-06-08 | PXD003405 | Pride
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