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ProteomicsMouse HiRIEF LCMS Proteomics of liver tissue - WT VS PolgA KO mutant
Mitochondrial dysfunction is implicated in aging and aging-related disorders, such as neurodegenerative diseases and stroke. To study the effects of progressive mitochondrial dysfunction, a homozygous knock-in mouse expressing a proof-reading deficient version of the nucleus-encoded catalytic subuni...
ORGANISM(S): Mus musculus (Mouse) 
2025-02-05 | PXD047574 | Pride
Mouse Tmt10plex Liver Wild type Hirief Lcms Murine Polga knockout Wt Qexactive 
TranscriptomicsExercise-induced mitochondrial translocation of p53 repairs mitochondrial DNA mutations
Exercise is a fundamental component of human health that is associated with greater life expectancy and reduced risk of chronic diseases. While the beneficial effects of endurance exercise on human health are well established, the molecular mechanisms responsible for these observations remain unclea...
ORGANISM(S): Mus musculus 
2015-12-11 | E-GEOD-75869 | biostudies-arrayexpress
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