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TranscriptomicsA large fraction of extragenic RNA Pol II transcription sites overlap enhancers
Mammalian genomes are pervasively transcribed outside mapped protein-coding genes. One class of extragenic transcription products is represented by long non-coding RNAs (lncRNAs), some of which result from Pol_II transcription of bona-fide RNA genes. Whether all lncRNAs described insofar are product...
ORGANISM(S): Mus musculus 
2010-05-21 | E-GEOD-20370 | biostudies-arrayexpress
GenomicsA large fraction of extragenic RNA Pol II transcription sites overlap enhancers (2)
Mammalian genomes are pervasively transcribed outside mapped protein-coding genes. One class of extragenic transcription products is represented by long non-coding RNAs (lncRNAs), some of which result from Pol_II transcription of bona-fide RNA genes. Whether all lncRNAs described insofar are product...
ORGANISM(S): Mus musculus 
2010-05-21 | E-GEOD-19991 | biostudies-arrayexpress
TranscriptomicsRNA-Seq profiling unveils a non-canonical Wnt signalling signature in pancreas versus liver fate decision
Understanding how distinct cell types arise from common multipotent progenitor cells is a major quest in stem cell biology. This knowledge will aid in the targeted differentiation and growth of stem cells, but also in the discovery of the basis of cellular plasticity and of how tissue programming ca...
ORGANISM(S): Mus musculus 
2013-09-11 | E-GEOD-40823 | biostudies-arrayexpress
MetabolomicsFSCN1 as a new druggable target in adrenocortical carcinoma

Adrenocortical carcinoma (ACC) is a rare endocrine malignancy with a high risk of relapse and metastatisation. The actin-bundling protein fascin (FSCN1) is overexpressed in aggressive ACC and represents a reliable prognostic indicator. FSCN1 has been shown to synergize with the Rho/Rac GEF VAV2 i...

2023-03-20 | MTBLS6402 | MetaboLights
TranscriptomicsChromatin immunoprecipitation of centromeric proteins CenpA and CenpC from human cell lines containing a neocentromere in band 13q21
Chromatin Immunoprecipitation of Centromeric Proteins, CenpA or CenpC, from human cell lines containing a neocentromere in band 13q21
ORGANISM(S): Homo sapiens 
2006-11-06 | E-TABM-168 | biostudies-arrayexpress
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