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MetabolomicsBacillus pacificus inhibits the vitamin absorption of jellyfish Aurelia coerulea polyp to reduce asexual reproduction (Polyps whole organism)

Symbiotic microorganisms play an important role in the growth and development of marine invertebrates, such as the sea moon, affecting their metamorphosis process. The outbreak of jellyfish puts pressure on marine ecosystems and affects their stability. However, researches on the development of j...

2024-06-03 | MTBLS9409 | MetaboLights
MetabolomicsBacillus pacificus inhibits the vitamin absorption of jellyfish Aurelia coerulea polyp to reduce asexual reproduction (Polyps culture media)

Symbiotic microorganisms play an important role in the growth and development of marine invertebrates, such as the sea moon, affecting their metamorphosis process. The outbreak of jellyfish puts pressure on marine ecosystems and affects their stability. However, researches on the development of j...

2024-06-03 | MTBLS9419 | MetaboLights
MetabolomicsSerum lipidomics study looking for specific endometrial polyps biomarkers distinguishing from endometrial cancer or hyperplasia

Endometrial diseases are common gynecological diseases that disorder women of childbearing age and perimenopausal women, including endometrial polyps (EP), endometrial cancer (EC), and endometrial hyperplasia (EH). Clinically, biopsy or imaging methods are usually used to screen and diagnose...

2022-01-14 | MTBLS3444 | MetaboLights
TranscriptomicsA global analysis of tandem 3'UTRs in eosinophilic chronic rhinosinusitis with nasal polyps
Background: Alternative polyadenylation (APA) is emerging as a widespread mechanism of gene regulation. The usage of APA sites allows a single gene to encode multiple mRNA transcripts with different 3'-untranslated region (3'UTR) lengths. Many disease processes reflect the importance of the regulati...
ORGANISM(S): Homo sapiens 
2012-12-31 | E-GEOD-39957 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of mouse intestinal polyps from Apc Delta14 strain treated with parecoxib
A "Cartes d'Identite des Tumeurs" (CIT) project from the french Ligue Nationale Contre le Cancer (http://cit.ligue-cancer.net). Comparison of mouse intestinal polyps response to parecoxib with controls.
ORGANISM(S): Mus musculus 
2009-05-31 | E-MEXP-2156 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of Mus musculus gastric Lkb1 polyps vs unaffected gastric Lkb1 mucosa
Gene expression in wildtype mouse stomach wall (n=6), Lkb1+/- mouse stomach wall (n=6) and Lkb1+/- mouse gastric polyps
ORGANISM(S): Mus musculus 
2010-10-06 | E-MEXP-2444 | biostudies-arrayexpress
TranscriptomicsAblation of Lgr5-positive cells in intestinal polyps from ApcMin;Lgr5DTR mice
We performed RNAseq on intestinal polyps from diptheria toxin-treated ApcMin;Lgr5DTR mice to investigate the effect of an acute selective pressure on stem cell populations in intestinal lesions. Lgr5+ cells in the ApcMin;Lgr5DTR mice were ablated with a single intraperitoneal dose of diphtheria toxi...
ORGANISM(S): Mus musculus 
2022-06-30 | E-MTAB-10470 | biostudies-arrayexpress
TranscriptomicsRNA-sequencing analysis of 5' capped RNAs identifies novel differentially expressed genes in sessile serrated colon polyps (SSPs)
RNA-sequencing of SSP RNA from patients with serrated polyposis syndrome identifies VSIG1 and MUC17 as potential diagnostic markers for SSPs 5' capped RNA from seven ascending SSPs, six patient matched uninvolved right colon and two normal right colon samples was used for RNA sequencing (15 samples ...
ORGANISM(S): Homo sapiens 
2014-04-29 | E-GEOD-46513 | biostudies-arrayexpress
TranscriptomicsAnalysis of colorectal tissue from APC- and MYH-associated polyposis patients
Expression profiling is a well established tool for the genome-wide analysis of the transcriptional activity of human neoplasia. However, the high sensitivity of this approach combined with the well-known cellular and molecular heterogeneity of cancer often result in extremely complex and extended e...
ORGANISM(S): Homo sapiens 
2008-04-01 | E-GEOD-9689 | biostudies-arrayexpress
TranscriptomicsStromal myofibroblasts drive tumorigenesis in Peutz-Jeghers Syndrome polyposis models
Germline mutations in LKB1 predispose to hereditary Peutz-Jeghers Syndrome (PJS), manifesting with gastrointestinal polyposis. We discovered that conditional deletion of Lkb1 in stromal fibroblasts using Fsp1-Cre leads to expansion of stromal cells and gastrointestinal polyposis in mice. Here we hav...
ORGANISM(S): Mus musculus 
2018-01-05 | E-MTAB-5549 | biostudies-arrayexpress
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