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GenomicsPolycomb associates genome-wide with a specific RNA polymerase II variant, and regulates metabolic genes in ES cells (ChIP-Seq)
Polycomb repressor complexes (PRCs) are important chromatin modifiers fundamentally implicated in pluripotency and cancer. Polycomb silencing in embryonic stem cells (ESCs) can be accompanied by active chromatin and primed RNA polymerase II (RNAPII), but the relationship between PRCs and RNAPII rema...
ORGANISM(S): Mus musculus 
2012-02-01 | E-GEOD-34518 | biostudies-arrayexpress
TranscriptomicsmRNA-seq and expression profile of mouse ES OS25 cells
mRNA-seq and expression profile of mouse ES OS25 cells Gene expression (mRNA-Seq) in mouse ES cells
ORGANISM(S): Mus musculus 
2012-02-01 | E-GEOD-34519 | biostudies-arrayexpress
GenomicsExpanding the CTD code: methylation of non-consensus Lysine residues marks early transcription in mammalian cells
Dynamic post-translational modification of RNA polymerase II (RNAPII) coordinates the co-transcriptional recruitment of enzymatic complexes that regulate chromatin states and co-transcriptional processing of nascent RNA. Extensive phosphorylation of serine residues occurs at the structurally-disorde...
ORGANISM(S): Mus musculus 
2015-12-22 | E-GEOD-72876 | biostudies-arrayexpress
TranscriptomicsEarly and late passage endothelial cells with or without PDCD10 downregulation
Primary cells deficient for PDCD10/CCM3 do not enter senescence as control cells. Microarray analysis was performed in cells transduced with non-targeting shRNA and CCM3 shRNA at passage 7 (early passage) and passage 11 (late passage), when control cells are already senescent. Primary endothelial ce...
ORGANISM(S): Homo sapiens 
2014-04-10 | E-GEOD-54095 | biostudies-arrayexpress
TranscriptomicsChIP-chip by array of mouse embryonic stem cells to analyze Jarid2 binding
Analysis of the binding of Jarid2 in mouse ES cells using a Flag tagged version of Jarid2 and a anti-Flag antibody.
ORGANISM(S): Mus musculus 
2010-04-13 | E-TABM-963 | biostudies-arrayexpress
UnknownExtensive folding variability between homologous chromosomes in mammalian cells
Not available
S-SCDT-10_1038-S44320-025-00107-3 | biostudies-other
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